Comparative study on medicinal materials,decoction pieces,standard decoction and formula granules of Radix Sophorae Tonkinensis based on fingerprint research
Objective To study the detection methods of main components in medicinal materials,decoction pieces,standard decoction and formula granules of Radix Sophorae Tonkinensis,so as to provide reference for the application of Radix Sophorae Tonkinensis formula granules.Methods HPLC was used to establish a fingerprint detection method for medicinal materials,decoction pieces,standard decoction and formula granules of Radix Sophorae Tonkinensis,and similarity evaluation,correlation analysis,cluster analysis and main component analysis were used for evaluation and analysis.Results There were five common characteristic peaks in the fingerprint chromatograms for medicinal materials,decoction pieces,standard decoction and formula granules of Radix Sophorae Tonkinensis,all of which were identified.Similarity evaluation and chemical pattern recognition research showed that there was no obvious difference between the four kinds.Conclusion The main components of medicinal materials,decoction pieces,standard decoction and formula granules of Radix Sophorae Tonkinensis are basically the same,which can provide reference for the basic research and clinical application research for formula granules of Radix Sophorae Tonkinensis.