首页|超微血流成像与彩色多普勒血流成像对慢性肾脏病肾血流灌注分析

超微血流成像与彩色多普勒血流成像对慢性肾脏病肾血流灌注分析

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目的 应用彩色多普勒血流成像(CDFI)和超微血流成像技术(SMI)评估慢性肾脏病(CKD)不同分期患者肾脏血流灌注情况的临床应用价值.方法 选取 2021 年 10 月至 2023 年 3 月在牡丹江医学院附属红旗医院肾内科住院诊断为CKD的患者 100 例,按照肾病预后质量指南(K/DOQI)将其分为四组(CKD 1~4 组).应用CDFI和SMI技术对肾脏血流灌注情况进行观察,对肾脏血流灌注应用Adler血流分型方法进行半定量评估,应用Mimics软件分析肾皮质感兴趣区血流灌注面积比(AR)进行定量评估,并对二者进行比较分析.结果 对CKD患者共 200 个肾脏进行血流灌注分型,SMI显示肾脏血流灌注分型为Ⅰ型的有 149 个,占比 74.5%,Ⅳ~Ⅴ型的有 2 个,占比 1%;CDFI显示肾脏血流灌注分型为Ⅰ型的有 83 个,占比 41.5%,Ⅳ~Ⅴ型的有 9 个,占比 4.5%.对CKD同一分期肾脏血流灌注分型比较,SMI在评价肾脏皮质血流灌注情况优于CDFI(P<0.05).应用CDFI、SMI技术对CKD各组间肾皮质感兴趣区AR进行比较,AR(SMI)高于AR(CDFI)(P<0.05).对CKD各组间AR(SMI)比较,CKD 1 组高于CKD 2~4组(P<0.05),CKD 2~3组高于CKD 4组(P<0.05),CKD 2~3组差异无统计学意义(P>0.05).结论 SMI技术对肾脏皮质血流灌注情况优于CDFI技术,可以更准确地评估CKD患者肾脏血流改变,具有较高临床应用价值.
Analysis of renal blood flow perfusion in chronic kidney disease using superb micro-vascular imaging and color Doppler flow imaging
Objective To evaluate the clinical application value of color Doppler flow imaging(CDFI)and superb micro-vascular imaging(SMI)in assessing renal blood flow perfusion in patients with chronic kidney disease(CKD)at different phases.Methods A total of 100 patients diagnosed with CKD who were hospitalized in the Department of Nephrology at Hongqi Hospital Affiliated to Mudanjiang Medical University from October 2021 to March 2023 were selected and divided into four groups(CKD 1-4 group)according to the kidney disease outcomes quality initiative(K/DOQI)guidelines.Observation of renal blood flow perfusion was conducted using CDFI and SMI techniques,semi-quantitative assessment of renal blood flow perfusion was conducted using Adler grade of blood flow,quantitative assessment was conducted on the area ratio(AR)of regions of interest of renal cortex using Mimics software,and comparative analysis of the two was conducted.Results 200 kidneys in the CKD patients were graded for blood flow perfusion.SMI showed that 149 kidneys were graded as typeⅠblood flow perfusion,accounting for 74.5%,and 2 kidneys were graded as type Ⅳ-Ⅴ,accounting for 1%.CDFI showed that 83 kidneys were graded as typeⅠ renal blood flow perfusion,accounting for 41.5%,and 9 kidneys were graded as type Ⅳ-Ⅴ,accounting for 4.5%.SMI was superior to CDFI in evaluating blood flow perfusion of the renal cortex in the same stage of CKD(P<0.05).CDFI and SMI techniques were used to compare the AR of regions of interest of the renal cortex in CKD groups,and AR(SMI)was higher than AR(CDFI)(P<0.05).When comparing the CKD groups,the AR(SMI)of the CKD 1 group was higher than that of the CKD 2-4 group(P<0.05),while the CKD 2-3 group was higher than that of the CKD 4 group(P<0.05).The difference in the CKD 2-3 group was not significant(P>0.05).Conclusion The SMI technique is superior to the CDFI technique in assessing blood flow perfusion of the renal cortex,and can more accurately assess renal blood flow changes in CKD patients,with high clinical application value.

Chronic kidney diseaseColor DopplerSuperb micro-vascular imagingUltrasound

张塞、孙源博、马小花、袁博、刘云双

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牡丹江医学院附属红旗医院超声科,黑龙江牡丹江 157011

牡丹江医学院附属红旗医院肾内科,黑龙江牡丹江 157011

慢性肾脏病 彩色多普勒 超微血流成像 超声

2024

中国医药科学
海峡两岸医药卫生交流协会 二十一世纪联合创新(北京)医药科学研究院

中国医药科学

影响因子:1.083
ISSN:2095-0616
年,卷(期):2024.14(9)