Analysis of renal blood flow perfusion in chronic kidney disease using superb micro-vascular imaging and color Doppler flow imaging
Objective To evaluate the clinical application value of color Doppler flow imaging(CDFI)and superb micro-vascular imaging(SMI)in assessing renal blood flow perfusion in patients with chronic kidney disease(CKD)at different phases.Methods A total of 100 patients diagnosed with CKD who were hospitalized in the Department of Nephrology at Hongqi Hospital Affiliated to Mudanjiang Medical University from October 2021 to March 2023 were selected and divided into four groups(CKD 1-4 group)according to the kidney disease outcomes quality initiative(K/DOQI)guidelines.Observation of renal blood flow perfusion was conducted using CDFI and SMI techniques,semi-quantitative assessment of renal blood flow perfusion was conducted using Adler grade of blood flow,quantitative assessment was conducted on the area ratio(AR)of regions of interest of renal cortex using Mimics software,and comparative analysis of the two was conducted.Results 200 kidneys in the CKD patients were graded for blood flow perfusion.SMI showed that 149 kidneys were graded as typeⅠblood flow perfusion,accounting for 74.5%,and 2 kidneys were graded as type Ⅳ-Ⅴ,accounting for 1%.CDFI showed that 83 kidneys were graded as typeⅠ renal blood flow perfusion,accounting for 41.5%,and 9 kidneys were graded as type Ⅳ-Ⅴ,accounting for 4.5%.SMI was superior to CDFI in evaluating blood flow perfusion of the renal cortex in the same stage of CKD(P<0.05).CDFI and SMI techniques were used to compare the AR of regions of interest of the renal cortex in CKD groups,and AR(SMI)was higher than AR(CDFI)(P<0.05).When comparing the CKD groups,the AR(SMI)of the CKD 1 group was higher than that of the CKD 2-4 group(P<0.05),while the CKD 2-3 group was higher than that of the CKD 4 group(P<0.05).The difference in the CKD 2-3 group was not significant(P>0.05).Conclusion The SMI technique is superior to the CDFI technique in assessing blood flow perfusion of the renal cortex,and can more accurately assess renal blood flow changes in CKD patients,with high clinical application value.