Influence of positioning error and safety of 3D printing compensation film in breast cancer radiotherapy
Objective To explore the positioning error and safety of the body surface covered with 3D printing compensation film after radiotherapy for breast cancer after radical surgery.Methods A total of 29 patients with breast cancer who received radiotherapy at the Binzhou Medical University Hospital from January to June 2023 were collected.The treatment methods included applying 3D tissue compensation membrane successively.The positioning error in the three-dimensional direction using images collected by the cone beam CT(CBCT)was analyzed and the external radiation range of the planned target volume(PTV)was calculated,as well as the incidence of acute radiation dermatitis.Results The clinical target volume(CTV)in the X,Y,and Z directions expanded to the PTV boundary at 0.94,0.84,and 0.52 cm,respectively.The positioning error of body mass index(BMI)<24 kg/m2 in the X-axis direction was greater than that in the other two groups,with statistically significant difference(P<0.05).The positioning error of≥28 kg/m2 in the Z-axis direction was smaller than that in the 24-28 kg/m2 group,with statistically significant difference(P<0.05).The initial positioning error in the X-axis direction was significantly smaller than that in the interval,with statistically significant difference(P<0.05).The incidence of grade 2 radiation dermatitis caused by the successive use of compensation films was 3.45%and 13.79%,respectively,with statistically significant difference(P<0.05).Conclusion For patients with a BMI<24 kg/m2,attention should be paid to the positioning in the X-axis direction;To avoid the occurrence of radiation dermatitis,try to add compensation film 15 times before the treatment.
Breast tumorsRadiotherapyConical beam CTPositioning errorBoundary expansion3D printing