Clinical observation on the impact of Zhentui Decoction on traditional Chinese medicine syndrome,exercise and life of Parkinson's disease with deficiency of both qi and blood
Objective To investigate the impact of Zhentui Decoction on traditional Chinese medicine(TCM)syndrome,exercise and life of Parkinson's disease with deficiency of both qi and blood.Methods A total of 72 patients with Parkinson's disease admitted to the Department of Geriatrics of Kunming Municipal Hospital of Traditional Chinese Medicine from August 2022 to July 2023 were selected and divided into the experimental group(n=36)and the control group(n=36)according to the random number table method.In them,the control group was treated with basic combined with western medicine,while the experimental group was treated with Zhentui Decoction on the basis of the control group.The clinical efficacy,TCM syndrome score,motor function,life ability score,quality of daily life(QoL)and adverse reactions(ADRs)of the two groups of patients were evaluated.Results The overall response rate of the experimental group was higher than that of the control group,with statistically significant difference(P<0.05).After 1,2 and 3 months of treatment,the TCM syndrome score,unified Parkinson's disease rating scale(UPDRS Ⅲ)score and PDQ-39 score of the experimental group were all lower than those of the control group,with statistically significant differences(P<0.05).During the treatment period,there were 2 cases of gastrointestinal reaction in the control group and 1 case in the experimental group,and no other obvious ADRs were found.There were no statistically significant differences between the two groups in ADRs(P>0.05).Conclusion Zhentui Decoction has a superior therapeutic efficacy on Parkinson's disease with deficiency of both qi and blood,which can reduce the score of TCM syndromes,improve the ability of QoL and motor function,with relatively higher safety and upgrade the QoL of patients.
Zhentui decoctionDeficiency of both qi and bloodParkinson's diseaseTraditional Chinese medicine syndromeMotor functionQuality of life
万方数据
维普
