Analysis on the distribution situation and impacting factors of multi drug resistance organism infection in intensive care unit
Objective To analyze the distribution situation and risk factors of multidrug resistant organism(MDRO)infection in patients of the intensive care unit(ICU),so as to put forward relevant prevention and control measures.Methods A total of 1407 patients admitted to the ICU of a tertiary first-class hospital in Shantou City from July 2021 to December 2022 were taken as the research object.The occurrence of MDRO infection during hospitalization was retrospectively collected,the incidence and distribution situation of MDRO infection were analyzed,and they were divided into the MDRO infection group and the non-MDRO infection group for comparison.Multivariate logistic regression was used to screen the related risk factors of MDRO infection.Results A total of 1407 inpatients of the ICU received bacterial culture and drug-resistant strains detection,including 880 male patients and 527 female patients.The incidence of MDRO infection was 18.69%(263/1407).MDRO infection strains of the ICU mainly involve Escherichia coli,Staphylococcus aureus and Klebsiella pneumoniae.The results of multivariate analysis showed that combined cardiovascular disease(OR=1.453,95%CI 1.006-2.079),duration of broad-spectrum antibiotic use was≥1 week(OR=1.900,95%CI 1.377-2.620),use of≥2 combined antibiotics(OR=1.913,95%CI 1.378-2.655),and indwelling intravascular catheters(OR=2.456,95%CI 1.416-3.241)were associated with an increased risk of MDRO infection(P<0.05).Conclusion The infection rate of MDRO of the ICU patients is still at a relatively high level compared with other general wards.According to the characteristics of MDRO infection and related high-risk factors,preventive and control measures should be taken in time to effectively reduce the infection rate of MDRO.
Intensive care unitMultiple drug resistant organismInfectionImpacting factor
万方数据
维普
