首页|应用CT量化指标CTPI与POLVI评价大叶性肺炎治疗效果的研究

应用CT量化指标CTPI与POLVI评价大叶性肺炎治疗效果的研究

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目的 研究大叶性肺炎病变总量与容积的计算机断层扫描(CT)量化指标及其与炎性检验指标的相关性,旨在评价该组CT量化指标在评估大叶性肺炎严重程度、预测疾病转归等方面的临床应用价值。方法 回顾性分析2018年1月至2022年10月在玉林市红十字会医院诊疗的71例大叶性肺炎患者共167例次CT胸部检查图像,采用计算机断层扫描肺炎指数(CTPI)、累及肺容积占比(POLVI)两个CT量化指标进行数据量化分析,获得病变加重组、好转组的日变化速率,并与检查同期(3 d内)的炎性检验指标进行比较及统计学分析。结果 CTPI好转组日变化速率中位数为[5。26(3。08,7。96)]%/d、加重组日变化速率中位数为[-5。04(-14。03,-3。49)]%/d;POLVI好转组日变化速率中位数为[4。34(2。14,7。31)]%/d、加重组日变化速率中位数为[-4。17(-28。33,-2。34)]%/d;该组CT量化指标与同期炎性检验指标血清淀粉样蛋白A、C反应蛋白显著相关(P<0。05);该组CT量化指标变化速率与血清淀粉样蛋白A、C反应蛋白、降钙素原、血沉变化率比较,差异无统计学意义(P>0。05)。结论 通过对CT检查的基础数据进行进一步量化处理,获得病灶CTPI、POLVI等CT量化指标数据,该组数据可精准评价大叶性肺炎的严重程度与变化速率,可在临床工作中推广应用。
Study on evaluation of efficacy of lobar pneumonia by CT quantitative indicators CTPI and POLVI
Objective To study the quantitative indicators of computed tomography(CT)for the total and volume of lesions in lobar pneumonia and their correlation with inflammatory test indicators,with the aim of evaluating the clinical application value of this group of CT quantitative indicators in evaluating the severity of lobar pneumonia and predicting disease outcomes.Methods A retrospective analysis was conducted based on 167 CT chest examination images of 71 patients with lobar pneumonia diagnosed and treated at the Red Cross Hospital of Yulin City from January 2018 to October 2022.The data were quantified using two CT quantitative indicators,namely CT pneumonia index(CTPI)and the proportion of lung volume involved(POLVI),to obtain the daily change rate of the aggravation group and the improvement group,and compare and statistically analyze the inflammatory test indicators during the same period of examination(within 3 days).Results For CTPI,the median daily change rate of the improvement group was(5.26[3.08,7.96])%/day,while the median daily change rate of the aggravation group was(-5.04[-14.03,-3.49])%/day.For POLVI,the median daily change rate in the POLVI improvement group was(4.34[2.14,7.31])%/day,while the median daily change rate in the aggravation group was(-4.17[-28.33,-2.34])%/day.The quantitative indicators of CT in this group were significantly correlated with the inflammatory test indicators of the same period,such as serum amyloid A and C-reactive protein(P<0.05).There were no significant differences between the change rate of CT quantitative indicators and the t-test of the change rate of serum amyloid A,C-reactive protein,procalcitonin and erythrocyte sedimentation rate(P>0.05).Conclusion By further quantifying the basic data of CT examination,CT quantitative indicators such as lesion CTPI and POLVI can be obtained to accurately evaluate the severity and the change rate of lobar pneumonia,which can be promoted and applied in clinical practice.

Lobar pneumoniaCTRadiodiagnosisQuantitative analysisPneumonia index

陈强、周颖、赖昌生、岑裕铭、吴碧玉

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玉林市红十字会医院放射科,广西玉林 537000

玉林市红十字会医院麻醉科,广西玉林 537000

玉林市红十字会医院科教科,广西玉林 537000

大叶性肺炎 计算机断层扫描 放射诊断 量化分析 肺炎指数

广西壮族自治区卫生健康委员会科研计划课题

Z-K20221822

2024

中国医药科学
海峡两岸医药卫生交流协会 二十一世纪联合创新(北京)医药科学研究院

中国医药科学

影响因子:1.083
ISSN:2095-0616
年,卷(期):2024.14(12)