Clinical study of pulmonary ventilation function and glucose and lipid metabolism in patients with IS combined with SAS
Objective To study pulmonary ventilation function and glucose and lipid metabolism in patients with ischemic stroke(IS)combined with sleep apnea syndrome(SAS).Methods A total of 54 patients with IS admitted to Jilin Neuropsychiatric Hospital from January to October 2022 were selected as the observation group.Depending on whether SAS was present,30 patients with simple IS were assigned to observation group 1,24 patients with IS combined with SAS were assigned to observation group 2,and 30 cases of healthy medical checkups in the same time period were selected as the control group.Retrospective analysis of general information,lung ventilation indicators,blood oxygen saturation,blood lipid levels,and insulin resistance(fasting insulin and insulin resistance index)indicators for all selected individuals were conducted.Results The total number of patients with hypertension,diabetes,and hyperlipidemia in the observation group 1 and 2 was higher than that in the control group,and the lung ventilation indicators and blood oxygen saturation were lower than those in the control group,with statistically significant differences(P＜0.05).Compared with observation group 2,observation group 1 had higher lung ventilation index and blood oxygen saturation index,with statistically significant differences(P＜0.05).The blood lipid indicators in the observation group 1 and 2 were not within the normal range,while the various indicators in the control group were within the normal range,and the low density lipoprotein cholesterol,total cholesterol,and triglyceride indicators were lower than those in the observation 1 and 2 group,and the high density lipoprotein cholesterol was higher than that in the observation group 1 and 2,with a statistically significant difference(P＜0.05).Compared with observation group 2,observation group 1 had better blood lipid indicators,with statistically significant differences(P＜0.05).The fasting insulin and insulin resistance index of the observation 1 and 2 group were both higher than the normal range,while the two indicators of the control group were both within the normal range and lower than the observation group 1 and 2 group,with statistically significant differences(P＜0.05).Compared with observation group 2,observation group 1 had lower fasting insulin and insulin resistance index,with statistically significant differences(P＜0.05).Conclusion IS patients with combined SAS have reduced pulmonary ventilation and worse glycolipid metabolism in the body.
Ischemic strokeSleep apnea syndromePulmonary ventilation functionGlucose and lipid metabolism
国家科技期刊平台
NSTL
万方数据
