首页|纳米孔测序检测嗜麦芽窄食单胞菌重症肺炎1例报告

纳米孔测序检测嗜麦芽窄食单胞菌重症肺炎1例报告

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嗜麦芽窄食单胞菌肺炎是一种因嗜麦芽窄食单胞菌感染所致的肺炎。采用传统病原菌培养法检测,阳性率低,假阴性率高、周期长,病原学证据短期内无法正确获得,影响预后。本文探讨一种较为快速准确的检测方法。纳米孔测序(NTS)是一种第三代测序技术,相比传统方法优点是它的成本和时间效益,吞吐量高。本文检测了 1例由嗜麦芽窄食单胞菌引起的重症肺炎。结果表明,该病是由嗜麦芽窄食单胞菌引起的感染。本文提供了 NTS可以快速识别病原体的证据,这对临床诊断和治疗具有重要意义。
Detection of severe pneumonia caused by Stenotrophomonas maltophilia by nanopore sequencing:a case report
Stenotrophomonas maltophilia pneumonia is a kind of pneumonia caused by Stenotrophomonas maltophilia infection.The conventional pathogen culture method for detection has a low positive rate,high false negative rate and a long cycle,and the pathogenic evidence cannot be accurately obtained in a short term,which affects the prognosis.This paper discussed a relatively faster and more accurate detection method.Being a third-generation sequencing technology,nanopore sequencing(NTS)has advantages over conventional methods in terms of cost and time efficiency,as well as high throughput.In this report,a case of severe hospital-acquired pneumonia caused by pseudomonas maltophilia was detected.The results indicated that the pathogen was caused by Stenotrophomonas maltophilia.This case report provides evidence that NTS can quickly identify pathogens,which is of great significance for clinical diagnosis and treatment.

Bacterial culturePneumoniaNanopore sequencingStenotrophomonas maltophilia

黄虎翔、梁超越、吴向春

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长江大学附属黄冈市中心医院呼吸与危重症医学科,湖北黄冈 438000

广西壮族自治区脑科医院重症医学科,广西柳州 545005

细菌培养 肺炎 纳米孔测序 嗜麦芽窄食单胞菌

湖北省卫生健康委员会青年医学拔尖人才计划

鄂卫通[2019]48号

2024

中国医药科学
海峡两岸医药卫生交流协会 二十一世纪联合创新(北京)医药科学研究院

中国医药科学

影响因子:1.083
ISSN:2095-0616
年,卷(期):2024.14(12)