The impact of reproductive tract microorganisms on endometrial receptivity and pregnancy outcomes of in vitro fertilization and embryo transfer
Endometrial receptivity(ER)is the key factor impacting the outcome of in vitro fertilization(IVF),and reproductive tract microorganisms affect ER.The research of vaginal microorganisms shows that the genus Lactobacillus is the dominant bacterial community in vagina,which plays an important role in maintaining the stability of vaginal microenvironment.The research on intrauterine microorganisms focuses on the etiology correlation between chronic endometritis and tumor,and the correlation research on the outcome of in vitro fertilization and embryo transfer(IVF-ET)is currently being studied.The microbiota dominated by lactobacillus(90％or more)is beneficial to the embryo implantation of infertile women undergoing IVF-ET,whereas the microbiota dominated by non-lactobacillus is related to adverse pregnancy outcomes such as embryo implantation failure and abortion.The reasons for the imbalance of intrauterine microbiota and its impact mechanism on ER need to be further studied,and how to regulate intrauterine microorganisms to facilitate the outcome of IVF-ET is still uncertain.This paper expound the characteristics of female reproductive tract microorganisms and their impact on women's health and assisted reproduction,so as to promote the development of reproductive technology.
万方数据
维普
