首页|益阳利水方治疗急性左心衰竭患者的疗效分析

益阳利水方治疗急性左心衰竭患者的疗效分析

扫码查看
目的 探讨益阳利水方对急性左心衰竭(ALHF)患者炎症指标、心肌损伤标志物、心功能及临床疗效的影响。方法 选取泰安市中医医院2022年5月至2023年5月收治的ALHF(阳虚水泛型)患者107例,按照随机数表法分成观察组54例和对照组53例,两组均给予常规西药治疗,观察组在对照组治疗的基础上给予益阳利水方。比较两组患者的炎症指标、心肌损伤标志物、心功能及临床疗效。结果 治疗后观察组的治疗总有效率(88。9%)优于对照组(73。6%),差异有统计学意义(P<0。05),治疗后,两组超敏C反应蛋白、白细胞介素-6、肌钙蛋白Ⅰ、肌酸激酶同工酶、N端脑钠肽前体、左室射血分数、左室收缩末期容积、左室舒张末期容积水平均较治疗前改善,观察组较对照组改善更明显(P<0。05)。结论 益阳利水方治疗ALHF可有效降低患者的血清相关炎症指标,降低心肌损伤标志物水平,改善心脏功能,提高生活质量,临床疗效良好。
Analysis of the therapeutic effect of Yiyang Lishui Formula on patients with acute left heart failure
Objective To explore the effect of Yiyang Lishui Formula on inflammatory indexes,myocardial injury markers,cardiac function and clinical efficacy in patients with acute left heart failure(ALHF).Methods A total of 107 patients with ALHF(Yang deficiency and water generalization)admitted to Taian Hospital of Traditional Chinese Medicine from May 2022 to May 2023 were divided into an observation group of 54 cases and a control group of 53 cases using a random number table method.Both groups received conventional Western medicine treatment,while the observation group received Yiyang Lishui Formula on the basis of the control group treatment.The inflammatory indexes,myocardial injury markers,cardiac function,and clinical efficacy between two groups of patients were compared.Results After treatment,the total effective rate of the observation group(88.9%)was higher than that of the control group(73.6%),and the difference was statistically significant cardiac(P<0.05).After treatment,the levels of high-sensitivity C-reactive protein,interleukin-6,troponin I,creatine kinase isoenzyme,N-terminal pro-brain natriuretic peptide,left ventricular ejection fraction,left ventricular end-systolic diameter and left ventricular end diastolic volume in the two groups improved compared to before treatment,and the observation group showed more significant improvement than the control group(P<0.05).Conclusion Yiyang Lishui Formula can effectively reduce serum-related inflammatory indexes,reduce the level of myocardial injury markers,improve the cardiac function,and enhance quality of life in patients with acute left heart failure,with good clinical effect.

Yiyang Lishui FormulaAcute left heart failureCardiac functionClinical efficacy

耿继飞、刘庆东

展开 >

山东省泰安市中医医院,山东泰安 271000

益阳利水方 急性左心衰竭 心功能 临床疗效

山东省中医药科技发展计划项目

2019-0760

2024

中国医药科学
海峡两岸医药卫生交流协会 二十一世纪联合创新(北京)医药科学研究院

中国医药科学

影响因子:1.083
ISSN:2095-0616
年,卷(期):2024.14(13)