Efficacy of glutamine combined with somatostatin and esomeprazole on patients with severe pancreatitis and its effect on serum inflammatory factors
Objective The of this study is to discuss the efficacy of the glutamine combined growth inhibitor,Esso Beauty,in the treatment of acute pancreatitis and its impact on the level of serum inflammatory cytokines.Methods A total of 120 patients with acute pancreatitis admitted to the Second Affiliated Hospital of Xiamen Medical College from January 2021 to January 2023 were randomly divided into a control group(n=60)and a treatment group(n=60).The control group was treated with esomeprazole,while the treatment group was treated with growth inhibitors and glutamine.The clinical efficacy of the two groups was compared.Results The total clinical effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).The serum indicators of the observation group were better than those of the control group,and the difference was statistically significant(P＜0.05).The intestinal mucosal barrier index in the observation group was better than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion The administration of glutamine,growth inhibitors and esomeprazole has been demonstrated to significantly improve inflammatory response and intestinal mucosal barrier function in patients with acute pancreatitis.
万方数据
维普
