Analysis of epidemiological and blood routine characteristics of 1416 children with herpetic angina
Objective To analyze the clinical features and blood routine characteristics of children with herpetic angina,so as to provide clinical reference for the diagnosis and treatment of herpetic angina.Methods The subjects were 1416 children with herpetic angina treated in the Pediatric Emergency Department of the Second Affiliated Hospital of Guangxi Medical University from June 2022 to May 2023.The basic case data of all children were acquired and blood samples were collected to detect the levels of white blood cell count(WBC),neutrophil percentage(NEU％)and high-sensitivity C-reactive protein(hs-CRP).100 children with WBC＞15 × 109/L were selected from the cases and divided into the observation group and the control group according to whether antibiotics were used or not.The clinical efficacy and WBC recovery of children in the observation group and the control group were compared.Results 1416 cases of herpetic angina mainly occurred in children aged 1-6 years,accounting for 87.43％of all the children admitted.The main clinical symptoms were fever,cough and poor appetite,while convulsion,vomiting and limb trembling were rare.The peak period of onset was from May to June,especially in June,with the highest incidence rate of 51.27％.The average WBC,NEU％and hs-CRP were(11.52±1.02)× 109/L,(71.78±4.95)％and(10.36±1.04)mg/L,respectively.These children were divided into＜1 year old,1-3 years old,4-6 years old and＞6 years groups old according to their age.The levels of WBC,NEU％and hs-CRP in the four groups were statistically different.After 5 d of treatment,the children with WBC＞15 × 109/L decreased in both groups,but there was no statistical difference between the two groups(P＞0.05).Conclusion The key population of herpetic angina is children aged 1-6 years,and the peak time is late spring and early summer.Therefore,prevention and control measures should be taken to reduce the incidence of herpetic angina.Symptoms such as fever,cough and poor appetite are common in clinic.The blood routine is characterized by a slight increase in WBC,NEU％and hs-CRP levels,so the increase of WBC alone cannot be used as the basis for the use of antibiotics for herpetic angina.
Herpetic anginaEpidemiological featuresCharacteristics of blood routineKey points of prevention and control
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