补肾活血法联合人工周期预防宫腔粘连分离术后复粘的meta分析
Meta-analysis of kidney tonifying and blood activating method combined with artificial cycles for preventing re-adhesion after transcervical resection of adhesion
王可 1徐杰2
作者信息
- 1. 湖南中医药大学研究生院,湖南长沙 410000
- 2. 湖南省常德市第一中医院妇产科,湖南常德 415000
- 折叠
摘要
目的 系统评价补肾活血法联合人工周期预防宫腔镜下宫腔粘连分离术(TCRA)后复粘的临床疗效.方法 收集万方数据知识服务平台、中国知网、维普网、PubMed、Embase、Cochrane Library,检索时间为2010年1月1日至2023年4月20日补肾活血法联合人工周期预防宫腔粘连分离术后复粘的随机对照试验,通过meta分析对纳入文献进行定量综合分析.结果 共纳入文献13篇,共包括1126例患者,其中观察组566例,对照组560例.meta分析结果显示,观察组的临床有效率、子宫内膜厚度、妊娠率高于对照组[RR=1.25,95％CI(1.17,1.34),P＜0.000 01;MD=1.24,95％CI(0.81,1.68),P＜0.000 01;RR=1.85,95％CI(1.45,2.35),P＜0.000 01];观察组的宫腔粘连评分、复粘率低于对照组[MD=-0.89,95％CI(-1.30,-0.47),P＜0.0001;RR=0.28,95％CI(0.15,0.50),P＜0.0001].结论 补肾活血法联合人工周期预防宫腔粘连分离术后复粘较单纯人工周期治疗更具有优势.
Abstract
Objective To systematically evaluate the clinical efficacy of kidney tonifying and blood activating method combined with artificial cycles for preventing re-adhesion after transcervical resection of adhesion(TCRA).Methods The randomized controlled trials of kidney tonifying and blood activating method combined with artificial cycles for preventing re-adhesion after transcervical resection of adhesion retrieved in Wanfang Data,CNKI,VIP,PubMed,Embase and Cochrane Library(the retrieval duration was from January 1,2010 to April 20,2023)were collected.A quantitative and comprehensive analysis of the included articles was conducted through meta-analysis.Results A total of 13 articles were included,including 1126 patients,including 566 in the observation group and 560 in the control group.Meta-analysis results showed that the clinical effective rate,endometrial thickness,and pregnancy rate of the observation group were higher than those of the control group(RR=1.25,95％CI[1.17,1.34],P＜0.000 01,MD=1.24,95％CI[0.81,1.68],P＜0.000 01,RR=1.85,95％CI[1.45,2.35],P＜0.000 01).The uterine adhesion score and re-adhesion rate in the observation group were lower than those in the control group(MD=-0.89,95％CI[-1.30,-0.47],P＜0.0001,RR=0.28,95％CI[0.15,0.50],P＜0.0001).Conclusion The kidney tonifying and blood activating method combined with artificial cycle therapy has advantages over simple artificial cycle therapy in preventing re-adhesion after transcervical resection of adhesion.
关键词
宫腔粘连/宫腔粘连分离术/补肾活血法/人工周期/meta分析Key words
Uterine adhesions/Transcervical resection of adhesion/Kidney tonifying and blood activating method/Artificial cycle/Meta-analysis引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据