Research progress on the synergistic metabolic pathways of blood lipids and lipid metabolism genes in endometrial cancer
Endometrial cancer is the sixth most common cancer in the world and also the most common gynecological malignancy in China.Most patients with endometrial cancer can be diagnosed in the early stages of the disease and have a good 5-year survival rate.However,about 30％of patients are still diagnosed in the late stage.At present,the treatment methods for endometrial cancer mainly focus on surgery and chemotherapy,but these treatments are not effective for advanced patients,resulting in a 5-year survival rate of only 30％-40％.Improving the late prognosis of endometrial cancer patients is an urgent problem to be solved.With the increasing attention paid to metabolomics,there is evidence that abnormal lipid metabolism is a more active metabolic change in cancer.In recent years,some domestic and foreign experts have found that lipid metabolism pathways play an important role in the prognosis of malignant tumor diseases.This paper mainly discusses the influence of blood lipids and lipid metabolism-related genes and pathways on the prognosis of endometrial cancer patients,provides some new ideas for the treatment target of endometrial cancer prognosis,further develops effective disease prevention measures and better therapeutic drugs,reduces the incidence rate of endometrial cancer,and improves the disease-free survival rate of endometrial cancer patients.
万方数据
维普
