With the rapid development of interventional and imaging diagnostic technologies,the application of contrast agents is becoming increasingly widespread.The risk that needs to be prevented is severe renal dysfunction associated with contrast agent drugs,namely contrast-induced nephropathy(CIN).CIN is the third leading cause of iatrogenic acute kidney injury,second only to severe acute kidney injury caused by insufficient renal blood perfusion and medication.If CIN occurs,it will increase the readmission rate of elderly patients after intervention surgery and affect their quality of life.The mechanism of CIN is still not fully understood,and currently,early prevention is the main approach with treatment as a supplement.There are many complications caused by contrast agents in clinical practice.Blindly canceling the contrast agent can lead to a lack of diagnostic data.Therefore,it is crucial to balance the relationship between obtaining the best imaging data and reducing the risk of CIN.