Advances in the diagnosis and treatment of ureaplasma urealyticum infection during perinatal period
Ureaplasma urealyticum is a common commensal in the female genital tract that can lead to fetal infection through vertical transmission.It is the main causative agent of chorioamnionitis and preterm labor.Antenatal,perinatal or postnatal transmission may result in neonatal ureaplasma infection.This may present as acute invasive infections such as pneumonia and sepsis,or as chronic inflammation such as bronchopulmonary dysplasia.Detection of ureaplasma urealyticum species is difficult and is not routinely done in clinical practice.Currently,there are no standardized criteria for the treatment of ureaplasma urealyticum infection in preterm infants.Meanwhile,whether treatment is necessary for ureaplasma urealyticum colonization in full-term neonates and during pregnancy is still unclear.This paper discusses the pathogenesis,clinical outcomes,and current advances in the diagnosis and treatment of ureaplasma urealyticum infection by reviewing the previous literature.
Ureaplasma urealyticumInfectionNeonatesPerinatal period