Research progress of exosomes from odontogenic mesenchymal stem cells in tissue regeneration
Regenerative medicine is dedicated to the study of how to promote tissue regeneration and functional reconstruction after trauma,primarily utilizing stem cell therapy and tissue engineering techniques to maintain,repair,regenerate,or improve the function of damaged tissues and organs.Mesenchymal stem cells are progenitor cells with multi-directional differentiation and regeneration abilities,widely used in the fields of regenerative medicine and tissue engineering.In particular,odontogenic mesenchymal stem cells have become the focus of research because of their convenient access and the absence of complex ethical issues.Odontogenic mesenchymal stem cells have various differentiation potentials and are considered as seed cells for tissue regeneration engineering,widely used in the fields of tissue engineering and regenerative medicine.In addition,mesenchymal stem cells can promote the regeneration and repair of damaged tissues through the paracrine pathway,in which exosomes are one of their main secretions.More and more evidence suggests that exosomes from odontogenic mesenchymal stem cells promote tissue regeneration in various disease and injury models.