Application of ciprofol in analgesia/anesthesia with bronchoscopy diagnosis and treatment
Objective To explore the safety of ciprofol in the application of analgesia/anesthesia with bronchoscopy diagnosis and treatment,and whether it can be a better choice to replace propofol.Methods A total of 63 patients who underwent elective bronchoscopy without intubation anesthesia in the endoscopy room of Weifang No.2 People's Hospital from November 2023 to January 2024 were selected.The patients were randomly divided into two groups using a digital randomization method:ciprofol group(n=32)and propofol group(n=31).The general information of the patient and the trend of changes in blood pressure(BP),heart rate(HR),and respiratory rate(RR)after entering the room,whether there was severe circulatory suppression,and whether additional medication was needed were recorded.Results There was no statistically significant difference in BP and HR between the two groups of patients during anesthesia(P>0.05),but the RR of ciprofol group was higher than that of propofol group at T1 and T4,and the difference was statistically significant(P<0.05).The comparison of additional medication between the two groups showed no statistically significant difference(P>0.05).The incidence of hypotension and bradycardia in ciprofol group was lower than that in propofol group,but only the difference in the incidence of bradycardia was statistically significant(P<0.05).Conclusion Ciprofol can significantly reduce respiratory depression and lower the incidence of hypotension and bradycardia in the analgesia/anesthesia with bronchoscopy diagnosis and treatment,but the dose of 0.3 mg/kg may need to be increased as appropriate.
CiprofolAnalgesia/anesthesia with bronchoscopy diagnosis and treatmentAdverse eventsDose
万方数据
维普
