Analysis of 13 respiratory pathogen infections and clinical indicators in Puning area
Objective To explore the infection status of 13 respiratory pathogens in Puning area and their relationship with clinical indicators.Methods A total of 411 patients with respiratory infection symptoms admitted to Puning People's Hospital from January to December 2023 were selected,and domestically produced 13 respiratory pathogen multiplex detection kits were used for pathogen detection using polymerase chain reaction(PCR)capillary electrophoresis fragment analysis.Results At least one pathogen was detected in 57.91%of patients,with the highest detection rate of rhinovirus.Adenovirus was prone to co-infection with other viruses.The infection rates of 7 viruses were compared among different age groups,and the difference was statistically significant(P<0.05).The positive rates of influenza A virus,seasonal H3N2 virus and influenza B virus were higher in autumn and winter,influenza A virus H1N1 and respiratory syncytial virus were higher in spring,and rhinovirus had the highest positivity rate in summer,with statistically significant difference(P<0.05).8 pathogens were significantly correlated with clinical indicators,and some laboratory indicators in each positive group were statistically different from those in the corresponding negative group(P<0.05).Conclusion Nasovirus and influenza A virus are the most common respiratory pathogen infections in Puning area.The infection rate of respiratory pathogens may vary by age and season,regardless of gender.Understanding the prevalence of respiratory pathogens and their relationship with clinical indicators can help prevent and treat respiratory infections more effectively.