Clinical comparison of EMR and ESD in the treatment of early intestinal cancer and high-grade intraepithelial neoplasia
Objective To investigate the effect of endoscopic mucosal resection(EMR)and endoscopic mucosal dissection(ESD)in patients with high-grade intraepithelial neoplasia and early intestinal cancer.Methods A total of 1 15 patients with high-grade intraepithelial neoplasia and early intestinal cancer admitted to the Department of Gastroenterology,the First People's Hospital of Zhaoqing from February 2021 to February 2023 were selected and randomly divided into an observation group(n=91)and a control group(n=24)according to different surgical methods.Patients in the control group received ESD operation,while patients in the observation group received EMR operation.After the operation,the perioperative situation of the two groups was collected,and the overall resection rate,complete resection rate,curative resection and complications were compared.Results There was no statistically significant difference in the incidence of bleeding 24 hours after surgery between the two groups of patients(P＞0.05).The observation group had shorter surgical duration and postoperative hospitalization days than the control group,and the hospitalization expenses of the observation group were also lower than those of the control group,with statistically significant differences(P＜0.05).The overall resection rate,complete resection rate,and curative resection rate of the observation group were higher than those of the control group,with statistically significant differences(P＜0.05).The total incidence of complications in the observation group was lower than that in the control group,with statistically significant difference(P＜0.05).Conclusion In contrast to ESD,EMR demonstrates efficacy in the management of early colorectal carcinoma and advanced intraepithelial lesions,enhancing the rates of intact removal,total excision,and therapeutic excision.This method also facilitates quicker patient recovery in the postoperative phase,reduces the duration of hospital stay,and cuts down on inpatient expenses,without elevating the likelihood of postoperative complications.Its clinical utility is evident,making it a technique that merits broader adoption and deployment.
万方数据
维普
