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自制外敷痛风方对急性痛风发作的疗效评价

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目的 评价自制外敷痛风方辅助治疗痛风急性发作的效果。方法 选取2022年6-12月因急性痛风性关节炎(AGA)发作在杭州市西溪医院住院患者80例,按照随机数表法分为对照组(n=40)和观察组(n=40)。对照组患者使用常规西药治疗方案(秋水仙碱、碳酸氢钠和塞来昔布),治疗组在对照组基础上加自制外敷痛风方进行治疗。比较两组的各项关节症状体征积分、整体疗效评价、患者满意度、达到有效标准所需时间以及血沉(ESR)、C反应蛋白(CRP)、血尿酸(UA)水平等。结果 治疗7 d后,观察组各项关节症状体征评分和ESR、CRP水平均低于对照组,差异有统计学意义(P<0。05)。观察组的总有效率高于对照组,差异有统计学意义(P<0。05),并且观察组达到有效标准所需时间短于对照组,差异有统计学意义(P<0。05)。观察组的治疗满意度明显高于对照组,差异有统计学意义(P<0。05)。结论 自制外敷痛风方辅助治疗痛风急性发作具有明显快速减轻临床症状,减轻炎症反应,副作用小等特点,值得临床推广。
Evaluation of efficacy of self-made external application of gout prescription on acute gout attack
Objective To evaluate the efficacy of self-made external application of gout prescription in adjuvant treatment of acute gout attack.Methods A total of 80 hospitalized patients with acute gouty arthritis(AGA)from June to December 2022 at Hangzhou Xixi Hospital were selected and randomly divided into a control group(n=40)and an observation group(n=40)using a random number table method.The patients in the control group were treated with conventional western medicine(colchicine,sodium bicarbonate and celecoxib),while the patients in the treatment group were treated with self-made gout prescription on the basis of the control group.The joint symptoms and signs scores,overall curative effect evaluation,patient satisfaction,effective time,erythrocyte sedimentation rate(ESR),C-reactive protein(CRP)and serum uric acid(UA)levels were compared between the two groups.Results After 7 days of treatment,the joint symptom and sign scores,ESR,and CRP levels in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The total effective rate of the observation group was higher than that of the control group,with a statistically significant difference(P<0.05),and the effective time of the observation group was shorter than that of the control group,with a statistically significant difference(P<0.05).The treatment satisfaction of the observation group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Self-made external application of gout prescription in the adjuvant treatment of acute gout attack has the characteristics of obviously relieving clinical symptoms quickly,relieving inflammatory reaction and having few side effects,which is worthy of clinical promotion.

External application of gout prescriptionAcute gouty arthritisAcute attackEfficacy evaluation

吴昊、姚怡梦、李儿

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杭州市西溪医院内分泌科,浙江 杭州 310009

外用痛风方 急性痛风性关节炎 急性发作 疗效评定

2024

中国医药科学
海峡两岸医药卫生交流协会 二十一世纪联合创新(北京)医药科学研究院

中国医药科学

影响因子:1.083
ISSN:2095-0616
年,卷(期):2024.14(19)