首页|基于脾肾互赞理论在糖尿病治疗中"肠-炎症-肾轴"机制的研究进展及理论依据

基于脾肾互赞理论在糖尿病治疗中"肠-炎症-肾轴"机制的研究进展及理论依据

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肠道菌群失衡被认为是糖尿病发展的一个重要因素。肠道微生物群的组成和功能失衡会影响胰岛素抵抗、葡萄糖代谢以及引发炎症,从而导致糖尿病的发作和进展。肠道菌群与糖尿病之间的关系是复杂的,尚未完全明确,需要更多的研究来阐明该机制,并制订针对肠道微生物群的有效策略来管理和预防糖尿病。"肠-肾轴"的提出为糖尿病带来全新的诊疗思路,其与中医脾肾互赞、脾肾相关、脾病及肾、肾病及脾等理论一致。本文将以脾肾互赞理论为基础,论述糖尿病的发生、发展和治疗,以期从"肠-炎症-肾轴"角度为糖尿病的防治提供新视角。
Research progress and theoretical basis of the mechanism of "intestine inflammation kidney axis" in the treatment of diabetes based on the theory of mutual praise between spleen and kidney
Imbalances in the gut microbiota are considered an important factor in the development of diabetes. The imbalance of the composition and function of intestinal microbiota will affect insulin resistance,glucose metabolism and triggers inflammation,which will lead to the onset and progress of diabetes. The relationship between gut microbiota and diabetes is complex and not yet fully understood. More research is needed to clarify specific mechanisms and develop effective strategies for managing and preventing diabetes targeting intestinal microbiota. The proposal of "intestine kidney axis" has brought a new diagnosis and treatment idea for diabetes,which coincides with the theory of mutual praise between spleen and kidney,spleen and kidney related,spleen disease and kidney,kidney disease and spleen in traditional Chinese medicine. This article discusses the development,onset and treatment of diabetes on the basis of mutual praise between spleen and kidney theory,in order to offer a new perspective on the prevention and treatment of diabetes from the point of view of the "intestine inflammation kidney axis".

DiabetesMutual praise between spleen and kidneyIntestine inflammation kidney axisIntestinal microbiotaTraditional chinese medicine

冯媛媛、张莉莉、马朝晖、曲静、张东鹏

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甘肃中医药大学,甘肃兰州 730050

甘肃中医药大学第一附属医院,甘肃兰州 730050

糖尿病 脾肾互赞 肠-炎症-肾轴 肠道微生物 中医

2024

中国医药科学
海峡两岸医药卫生交流协会 二十一世纪联合创新(北京)医药科学研究院

中国医药科学

影响因子:1.083
ISSN:2095-0616
年,卷(期):2024.14(20)