Research progress on the mechanism of decidual natural killer cells in the placenta formation
Decidual natural killer (dNK) cells account for 70％ of decidual immune cells in early pregnancy and are the largest lymphocyte subpopulation found in decidua. In the process of placenta formation,dNK cells can promote the migration of extravillous trophoblasts (EVTs) to the maternal uterus and change its blood vessels through various functions,among which the remodeling of the uterine spiral artery by EVTs is crucial for placenta formation. dNK cells can also protect against placental infection through their cytotoxic effects,thus ensuring the healthy growth and development of the fetus. This paper provides a brief summary of the latest research progress on the mechanism of dNK cells in placental formation,hoping to provide theoretical basis for future clinical diagnosis and treatment.
万方数据
维普
