Effect of Hp infection on gastric mucosal barrier and the intervention effect of probiotics
Nearly half of the global population is infected with helicobacter pylori (Hp),China is a country with a high incidence of Hp infection. Chronic gastritis is the most common digestive system disease in the Chinese population,Hp infection is the main cause of its occurrence,and some Hp infected individuals may develop gastric mucosal atrophy and/or intestinal metaplasia on the basis of chronic gastritis,further increasing the risk of gastric cancer. The gastric mucosal barrier is the body's first line of defense against Hp,including the mucus bicarbonate barrier,epithelial barrier,microcirculation barrier,biological barrier,and immune barrier. The destruction of its structure and function plays an important role in the occurrence and development of Hp gastritis. Probiotics play an important role in the treatment of Hp gastritis by enhancing the gastric mucosal barrier,increasing the eradication rate of Hp,and reducing treatment-related side effects. This article provides a comprehensive analysis of the impact of Hp infection on the gastric mucosal barrier and the intervention effect of probiotics,providing a scientific basis for the prevention and treatment of Hp gastritis.
万方数据
维普
