Clinical efficacy of Huangqi Yishen granules in treating type Ⅱ cardiorenal syndrome of Yang deficiency syndrome
Objective To study the clinical efficacy of Huangqi Yishen granules in treating type Ⅱ cardiorenal syndrome (CRS) with Yang deficiency syndrome. Methods A prospective randomized controlled study was conducted in this study. A random number table method was used to divide 110 patients with type Ⅱ CRS of Yang deficiency syndrome in the Cardiovascular Department,Guangdong Second Traditional Chinese Medicine Hospital (Baiyun District) from September 2021 to August 2023 into two groups,with 55 cases in each group. The control group received routine western medicine treatment,while the treatment group was treated with Qiyishen granules 1 pack of tid on the basis of the control group,with a treatment course of 4 weeks. The traditional Chinese medicine syndrome score,heart function index,kidney function index,inflammation index,and incidence of adverse reactions were compared between the two groups. Results After 2 courses of treatment,the scores of traditional Chinese medicine symptoms in the treatment group were lower than those in the control group,and the difference was statistically significant (P<0.05). The left ventricular ejection fraction,ventricular shortening rate,and early diastolic peak velocity/late diastolic tissue velocity in the treatment group were higher than those in the control group,and the differences were statistically significant (P<0.05). The levels of cystain C,serum creatinine and blood urea nitrogen in the treatment group were lower than those in the control group,and the differences were statistically significant (P<0.05). The levels of white blood cell count,neutrophil count and hypersensitivity C-reactive protein in the treatment group were lower than those in the control group,and the differences were statistically significant (P<0.05). There were no obvious adverse reactions in both groups during treatment. Conclusion Huangqi Yishen granules can improve traditional Chinese medicine syndrome and heart and kidney function in type Ⅱ CRS patients with Yang deficiency syndrome,reduce inflammatory reactions,and have high safety,which is worth promoting.
Yang deficiency syndromeType Ⅱ cardiorenal syndromeHuangqi Yishen granulesHeart functionKidney functionInflammationSafety
万方数据
维普
