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预后营养指数对老年患者医院感染特征的影响

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目的 评估预后营养指数(PNI)对老年患者医院感染特征的影响。方法 选取2021年1—12月在江苏大学附属武进医院住院的老年医院感染患者237例(男156例,女81例),平均年龄(69。81±10。15)岁。收集患者的一般资料及实验室检查结果,计算中性粒细胞与淋巴细胞比率(NLR)、血小板与淋巴细胞比率(PLR)、淋巴细胞与单核细胞比率(LMR)及PNI。以PNI≥45及<45为两组,高PNI组47例,低PNI组190例。结果 医院感染前三位的部位为下呼吸道、泌尿道及手术切口。logistic回归结果显示,影响医院感染预后的因素主要包括是否合并感染入院及PNI值(P<0。05)。PNI分组后发现,导致预后不良的低PNI组年龄更大,住院天数更长,白蛋白、总胆固醇、甘油三酯、低密度脂蛋白胆固醇、尿酸及LMR更低,NLR、PLR更高,差异有统计学意义(P<0。05)。低PNI组手术及侵袭性操作比率高,差异有统计学意义(P<0。05)。结论 PNI对老年住院患者医院感染特征有一定的影响,在关注所有医院感染因素时,对低PNI患者尤其要关注手术、侵袭性操作及炎症因素。
Influence of prognostic nutritional index on the characteristics of nosocomial infection in elderly patients
Objective To evaluate the influence of prognostic nutrition index (PNI) on the characteristics of nosocomial infection in elderly patients. Methods A total of 237 patients (156 males and 81 females) with nosocomial infection were enrolled in Wujin Hospital Affiliated with Jiangsu University from January to December 2021,with an average age of (69.81±10.15) years old. General data and laboratory results were collected,and neutrophil to lymphocyte ratio (NLR),platelet to lymphocyte ratio (PLR),lymphocyte to monocyte ratio (LMR) and PNI were calculated. PNI ≥ 45 and<45 were divided into two groups:high PNI group (47 cases) and low PNI group (190 cases). Results The top three sites of nosocomial infection were lower respiratory tract,urinary tract and surgical incision. logistical regression found that the main factors affecting the prognosis of nosocomial infection were whether the patients were hospitalized with infection and PNI value (P<0.05). After PNI grouping,it was found that the low PNI group leading to poor prognosis was older,longer in hospital stay,lower in albumin,total cholesterol,triglyceride,low density lipoprotein cholesterol,uric acid and LMR,and higher in NLR and PLR,with statistical significance (P<0.05). The rate of operation and invasive operation in low PNI group was higher,and the difference was statistically significant (P<0.05). Conclusion PNI has a certain influence on the characteristics of nosocomial infection in elderly inpatients. When paying attention to all nosocomial infection factors,surgery,invasive operation and inflammatory factors should be paid special attention to the low PNI patients.

Prognostic nutritional indexNosocomial infectionNeutrophil to lymphocyte ratioPlatelet to lymphocyte ratioLymphocyte to monocyte ratio

邵雪景、徐瑞君、杨奇超、华枫

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江苏大学附属武进医院 徐州医科大学武进临床学院,江苏常州 213000

江苏省常州市武进区遥观镇卫生院,江苏常州 213000

预后营养指数 医院感染 中性粒细胞与淋巴细胞比率 血小板与淋巴细胞比率 淋巴细胞与单核细胞比率

2024

中国医药科学
海峡两岸医药卫生交流协会 二十一世纪联合创新(北京)医药科学研究院

中国医药科学

影响因子:1.083
ISSN:2095-0616
年,卷(期):2024.14(20)