Influence of prognostic nutritional index on the characteristics of nosocomial infection in elderly patients
Objective To evaluate the influence of prognostic nutrition index (PNI) on the characteristics of nosocomial infection in elderly patients. Methods A total of 237 patients (156 males and 81 females) with nosocomial infection were enrolled in Wujin Hospital Affiliated with Jiangsu University from January to December 2021,with an average age of (69.81±10.15) years old. General data and laboratory results were collected,and neutrophil to lymphocyte ratio (NLR),platelet to lymphocyte ratio (PLR),lymphocyte to monocyte ratio (LMR) and PNI were calculated. PNI ≥ 45 and<45 were divided into two groups:high PNI group (47 cases) and low PNI group (190 cases). Results The top three sites of nosocomial infection were lower respiratory tract,urinary tract and surgical incision. logistical regression found that the main factors affecting the prognosis of nosocomial infection were whether the patients were hospitalized with infection and PNI value (P<0.05). After PNI grouping,it was found that the low PNI group leading to poor prognosis was older,longer in hospital stay,lower in albumin,total cholesterol,triglyceride,low density lipoprotein cholesterol,uric acid and LMR,and higher in NLR and PLR,with statistical significance (P<0.05). The rate of operation and invasive operation in low PNI group was higher,and the difference was statistically significant (P<0.05). Conclusion PNI has a certain influence on the characteristics of nosocomial infection in elderly inpatients. When paying attention to all nosocomial infection factors,surgery,invasive operation and inflammatory factors should be paid special attention to the low PNI patients.
Prognostic nutritional indexNosocomial infectionNeutrophil to lymphocyte ratioPlatelet to lymphocyte ratioLymphocyte to monocyte ratio