Diagnostic value of right subclavian artery intima-media thickness combined with laboratory indexes in patients with hypertension complicated with coronary heart disease
Objective To explore the diagnostic value of right subclavian artery intima-media thickness (IMT) combined with laboratory indexes in patients with hypertension complicated with coronary heart disease. Methods A total of 200 patients with primary hypertension who underwent physical examination at the Tenth Affiliated Hospital of Southern Medical University from August 2020 to July 2021 were divided into the hypertension group (n=142) and the hypertension complicated with coronary heart disease group (n=58). The differences in basic data,right subclavian artery IMT,and laboratory index levels were compared to analyze the risk factors for hypertension patients complicated with coronary heart disease,and the auxiliary diagnostic value of right subclavian artery IMT combined with laboratory indexes for concurrent coronary heart disease. Results There was no statistically significant difference in gender,age,diastolic blood pressure,systolic blood pressure,smoking,and alcohol consumption distribution between the two groups (P>0.05). The IMT value of the right subclavian artery,fasting plasma glucose (FPG),low-density lipoprotein cholesterol (LDL-C),and homocysteine (Hcy) of patients with hypertension complicated with coronary heart disease were higher than those of patients with hypertension,and the difference was statistically significant (P<0.05). There was no statistically significant difference in the levels of triglycerides (TG),total cholesterol (TC),high-density lipoprotein cholesterol (HDL-C),serum creatinine (Scr),and blood urea nitrogen (BUN) between the two groups of patients (P>0.05). Logistic regression analysis showed that higher IMT value,higher FPG level,higher LDL-C level and higher Hcy level of right subclavian artery were independent risk factors for hypertension patients complicated with coronary heart disease (P<0.05). The area under the curve (AUC) of right subclavian artery IMT combined with laboratory indexes in predicting hypertension patients complicated with coronary heart disease was 0.838,with corresponding sensitivity of 89.74％,respectively,which was better than single indexes (P<0.05). Conclusion High right subclavian artery IMT is an independent risk factor for coronary heart disease in patients with primary hypertension,and its role in early assessment of coronary heart disease complications is clear when combined with laboratory indexes.
万方数据
维普
