Practice of constructing the clinical rational use and management system of key monitoring drugs based on multi-departmental collaboration mode
Objective To explore the construction of a clinical rational use and management system for key monitored drugs based on the multi-departmental and multi-disciplinary collaboration mode,and to provide reference for medical institutions to manage key monitored drugs. Methods Based on the multi-departmental and multi-disciplinary collaboration mode,a key monitoring drug clinical rational use and management system was constructed,and the drugs listed in the key monitoring drug catalog of Loudi Central Hospital (hereinafter referred to as "our hospital") were fully managed. Statistics and analysis were made on the sales amount of key monitored drugs,the proportion of drugs,the clinical irrational use rate and the number of cases of adverse reactions reported before and after the establishment of the clinical rational use and management system from February to November 2023. According to the review results,the rules of key monitored drugs were finely set in the pre-trial prescription system,and their practical effects were evaluated. Results Since the implementation of the key monitoring drug supervision in July 2023,the proportion of drugs listed in our hospital's key monitoring catalogue showed a downward trend,from 12.07% to 9.61%. The decline was 20.38%. Clinical irrational use rate decreased significantly,from 17.75% to 6.33%,down by 11.42%. The number of reported cases of adverse reactions involving key monitored drugs decreased significantly,from 58 cases to 31 cases and the difference before and after supervision was statistically significant (P<0.05). Conclusion Based on the multi-departmental and multi-disciplinary collaboration mode,the rational clinical use and management system of key monitoring drugs was established,which significantly reduced the irrational clinical use of key monitoring drugs in our hospital,reduced the economic burden of patients,reduced adverse reactions and promoted the rational clinical use of drugs.
Multi-departmental and multi-disciplinary collaborationKey monitoring drugsRational use of drugsManagement system