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基于多部门协作模式构建重点监控药品临床合理使用及管理体系的实践

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目的 探讨基于多部门多学科协作模式构建重点监控药品临床合理使用及管理体系,为医疗机构管理重点监控药品提供参考。方法 基于多部门多学科协作模式构建重点监控药品临床合理使用及管理体系,对娄底市中心医院(以下简称"本院")重点监控药品目录内药品施行全程管理。统计并分析2023年2—11月构建临床合理使用及管理体系前后的重点监控药品销售金额占比、临床不合理使用率,不良反应报告例数,并根据点评结果在前置审方系统中对重点监控药品进行规则的精细化设置,评价其实践效果。结果 自2023年7月实施重点监控药品监管后,纳入本院重点监控目录的药品销售金额药占比呈下降趋势,由12。07%下降为9。61%。降幅为20。38%;临床不合理使用率显著下降,由17。75%降至6。33%,下降了11。42%。涉及重点监控药品的不良反应报告例数明显减少,由58例降至31例,监管前后的差异有统计学意义(P<0。05)。结论 基于多部门多学科协作模式构建重点监控药品临床合理使用及管理体系,显著减少本院临床对重点监控药品不合理使用情况,减轻患者经济负担,降低不良反应,促进临床合理用药。
Practice of constructing the clinical rational use and management system of key monitoring drugs based on multi-departmental collaboration mode
Objective To explore the construction of a clinical rational use and management system for key monitored drugs based on the multi-departmental and multi-disciplinary collaboration mode,and to provide reference for medical institutions to manage key monitored drugs. Methods Based on the multi-departmental and multi-disciplinary collaboration mode,a key monitoring drug clinical rational use and management system was constructed,and the drugs listed in the key monitoring drug catalog of Loudi Central Hospital (hereinafter referred to as "our hospital") were fully managed. Statistics and analysis were made on the sales amount of key monitored drugs,the proportion of drugs,the clinical irrational use rate and the number of cases of adverse reactions reported before and after the establishment of the clinical rational use and management system from February to November 2023. According to the review results,the rules of key monitored drugs were finely set in the pre-trial prescription system,and their practical effects were evaluated. Results Since the implementation of the key monitoring drug supervision in July 2023,the proportion of drugs listed in our hospital's key monitoring catalogue showed a downward trend,from 12.07% to 9.61%. The decline was 20.38%. Clinical irrational use rate decreased significantly,from 17.75% to 6.33%,down by 11.42%. The number of reported cases of adverse reactions involving key monitored drugs decreased significantly,from 58 cases to 31 cases and the difference before and after supervision was statistically significant (P<0.05). Conclusion Based on the multi-departmental and multi-disciplinary collaboration mode,the rational clinical use and management system of key monitoring drugs was established,which significantly reduced the irrational clinical use of key monitoring drugs in our hospital,reduced the economic burden of patients,reduced adverse reactions and promoted the rational clinical use of drugs.

Multi-departmental and multi-disciplinary collaborationKey monitoring drugsRational use of drugsManagement system

李元林、杨琼、陈小华、张秀芹

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湖南省娄底市中心医院药剂科,湖南娄底 417000

多部门多学科协作 重点监控药品 合理用药 管理体系

2024

中国医药科学
海峡两岸医药卫生交流协会 二十一世纪联合创新(北京)医药科学研究院

中国医药科学

影响因子:1.083
ISSN:2095-0616
年,卷(期):2024.14(20)