Research status quo of function mechanism of Chinese herbal medicines containing active ingredients on osteoporosis
Osteoporosis(OP)is a systemic disease,which is prone to fracture due to the continuous decline of bone mass and the increase of bone brittleness with age.With the aging of population in modern society,the prevalence of OP is rising,and this problem has gradually become a hot spot.It is found that some active ingredients contained in Chinese herbal medicines such as Epimedium brevicornu Maxim.,Psoralea corylifolia Linn.,Davallia trichomanoides Blume,Curculigo orchioides Gaertn.,Ligustrum lucidum Ait.,Eclipta prostrata(L.)L.and Eucommia ulmoides Oliv can improve bone mineral density,reduce bone resorption,and further reduce the possibility of osteoporotic fracture,which has a certain therapeutic efficacy on OP.In this paper,the bioactive components contained in Chinese crude drug are reviewed,which have the functions of anti-inflammation,inhibiting osteoclast production,promoting osteoblast development and relieving OP,so as to provide some reference for the rational application of Chinese materia medica in clinical treatment of OP.
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