Analysis of the correlation between the increase of hemoglobin level and related physical examination indices and risk factors in healthy adult men
Objective To investigate the correlation between the increase of hemoglobin(Hb)level and urea(UREA),creatinine(CREA),uric acid(UA),homocysteine(HCY)and thyroid stimulating hormone(TSH)and the risk factors in healthy adult men.Methods A total of 502 healthy adult male examinees from the First Affiliated Hospital of Guangxi Medical University from January to December,2022 were randomly selected as the research objects.According to the Hb concentration of the examinees,those were divided into the Hb-increase group(n=251,Hb＞160 g/L)and the Hb-normal group(n=251,120 g/L ≤ Hb ≤ 160 g/L).The levels of UREA,CREA,UA,HCY and TSH were detected and statistically analyzed.Results The level of UREA in the Hb-increase group was lower than those in the Hb-normal group,and the levels of UA and HCY in the Hb-increase group were higher than those in the Hb-normal group,with statistically significant differences(P＜0.05).The incidence of abnormal HCY in the Hb-increase group was higher than that in the normal group,with statistically significant difference(P＜0.05).Binary Logistic regression analysis showed that the occurrence of high Hb was negatively correlated with URA(OR=0.810,95％CI:0.693-0.946),but positively correlated with UA(OR=1.003,95％CI:1.001-1.005)and HCY(OR=1.090,95％CI:1.044-1.139).The decrease in UREA levels and the increase in UA and HCY levels were independent risk factors for increased Hb levels in healthy adult males(P＜0.05).Conclusion There may be many kinds of disease risks when the healthy adult male's Hb＞160 g/L,so it is necessary to evaluate the cardiovascular and cerebrovascular functions,liver and kidney functions in time,and take preventive intervention measures to really reduce the disease risk.
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