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子宫内膜癌临床病理特点及发病变化趋势分析

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目的 分析子宫内膜癌临床病理特点及发病变化趋势.方法 选取2013年1月至2023年8月在三明市第二医院和福建省妇幼保健院就诊的1112例患者,调取临床资料开展分析.结果 2013-2023年患病例数逐年递增,且发病年龄趋于年轻化;1112例患者年龄18~85岁,平均(52.13+9.50)岁,49-59岁是发病的高峰期,有444例,占总患病例数的39.93%;≤45岁患者668例,占总患病例数的60.07%,在该年龄区间的患者例数逐年递增,且在总患病例数中的占比逐年上升,差异有统计学意义(P<0.05).子宫内膜样腺癌1075例,占总患病例数的96.67%;非子宫内膜样腺癌37例,占总患病例数的3.33%.相较于子宫内膜样腺癌,在非子宫内膜样腺癌中G3、深肌层浸润的占比相对较高;从手术-病理分期看,非子宫内膜样腺癌中Ⅲ、Ⅳ期占比相对较高,差异有统计学意义(P<0.05).结论 子宫内膜癌发病率逐年增高,且发病人群趋于年轻化;其中非子宫内膜腺癌分化程度较低,且有着较强的侵袭性,预后差,应当予以重视.
Analysis of clinical and pathological characteristics and incidence trend of endometrial carcinoma
Objective To analyze the clinical and pathological characteristics and the incidence trend of endometrial carcinoma.Methods A total of 1112 patients who visited Second Hospital of Sanming and Fujian Provincial Maternity and Child Health Hospital from January 2013 to August 2023 were selected,and clinical data were collected for analysis.Results The number of cases increased year by year from 2013 to 2023,and the age of onset tended to be younger.1112 patients were aged 18-85 years,with an average of(52.13±9.50)years,and 49-59 years old was the peak period of onset,with 444 cases accounting for 39.93%of the total number of cases.There were 668 cases of patients≤45 years old,accounting for 60.07%of the total number of diseased cases.The number of patient cases in this age range increased year by year,and the proportion of the total diseased cases increased year by year,and the difference was statistically significant(P<0.05).There were 1075 cases of endometrioid adenocarcinoma,accounting for 96.67%of the total number of cases,and 37 cases of non-endometrioid adenocarcinoma,accounting for 3.33%of the total number of cases.Compared with endometrioid adenocarcinoma,among non-endometrioid adenocarcinomas,the proportion of G3 and deep myometrial infiltration was relatively high.In terms of surgical-pathologic staging,the proportion of stage Ⅲ and Ⅳ in non-endometrioid adenocarcinomas was relatively high,and the difference was statistically significant(P<0.05).Conclusion The incidence of endometrial carcinoma is on the rise,and the population tends to be younger.Among them,non-endometrial adenocarcinoma has a lower degree of differentiation,strong invasion and poor prognosis,so it should be taken seriously.

Endometrial carcinomaClinical characteristicsPathological characteristicsOnset age

陈海燕、蔡琳、黄扬杰、郑辉

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福建省三明市第二医院妇科,福建永安 366000

福建省三明市第二医院血管外科,福建永安 366000

福建省妇幼保健院妇二科,福建 福州 350001

子宫内膜癌 临床特点 病理特点 发病年龄

2024

中国医药科学
海峡两岸医药卫生交流协会 二十一世纪联合创新(北京)医药科学研究院

中国医药科学

影响因子:1.083
ISSN:2095-0616
年,卷(期):2024.14(22)