Preparation and performance of Sapindus mulorossi oil skin care emulsion
In order to promote the application research of Sapindus mulorossi oil in cosmetics,nanoemulsion was prepared with Sapindus mulorossi oil as raw material,and with particle size and Zeta potential as indicators,the preparation process conditions of nanoemulsion were optimized by single factor experiment.Then,the Sapindus mulorossi oil skin care emulsion was prepared based on the single factor experiment.The stability,safety,antioxidant activity,moisturizing properties,tyrosinase inhibitory activity and UV absorption effect of the skin care emulsion were evaluated with olive oil skin care emulsion and commercial skin care emulsion as control.The results showed that the optimal conditions for preparing nanoemulsion of Sapindus mulorossi oil were obtained as follows:dosage of compound emulsifier(volume ratio of Tween-60 to Span A83 3∶1)8％,dosage of co-emulsifier 6％,dosage of Sapindus mulorossi oil 2％or 4％,emulsification temperature 70 ℃ and shear rate 12 000 r/min.The stability and safety of three skin care emulsions RY-1(dosage of Sapindus mulorossi oil 2％)、RY-2(dosage of Sapindus mulorossi oil 4％)and RY-3(dosage of olive oil 2％)were good.The EC50 of the three emulsions for scavenging DPPH· was61.5,55.7 μg/mL and 58.1 μg/mL,the EC50for scavenging ABTS+·was 58.3,50.1 μg/mLand 53.5 μg/mL,the EC50for scavenging·OH was 59.7,30.2 μg/mL and 59.9 μg/mL,the EC50for scavenging O2-·was 59.6,41.8 μg/mL and 57.3 μg/mL,the EC50for inhibiting the activity of tyrosinase was 147.5,118.6 μg/mL and 140.2 μg/mL,respectively.At RH 43％and 81％,the order of moisturization rate of the 4 skin care emulsions both were RY-2＞commercial skin care emulsion＞RY-3＞RY-1.The Sapindus mulorossi oil skin care emulsion had certain UV absorption capacity.In conclusion,the formula of RY-2 is better than RY-1 and RY-3.The Sapindus mulorossi oil skin care emulsion is safe,non-irritating,and has certain antioxidant activity,which has good application prospects.
Sapindus mulorossi oilskin care emulsionstabilitysafetymoisturizing propertyantioxidant activityinhibitory rate of tyrosinase activityUV absorption effect
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