Association between branched/odd-chain fatty acids and intestinal health
To ascertain the effects of branched-chain fatty acids(BCFA)and odd-chain fatty acids(OCFA)on intestinal health,serum fatty acid contents in healthy population and patients with intestinal diseases were measured by gas chromatography-mass spectrometry.Orthogonal partial least-squares discrimination analysis(OPLS-DA)was used to identify characteristic fatty acid of intestinal healthy population.The results showed that 9 kinds of BCFA and 4 kinds of OCFA were detected in the healthy control group,intestinal polyp group and colorectal cancer group.The contents of BCFA and OCFA were significantly higher in healthy population(p＜0.05),and the contents of anteiso-C17∶0 and C17∶0 showed a gradient decreasing trend with the deterioration of intestinal health status(p＜0.05).OPLS-DA identified six characteristic fatty acid markers of anteiso-C17∶0,iso-C17∶0,C18∶1,C18∶0,C16∶0 and C14∶0.To sum up,BCFA and OCFA have a potential protective effect on intestinal health.
branched-chain fatty acidsodd-chain fatty acidsintestinal health
NETL
NSTL
万方数据
