EB病毒阳性弥漫大B细胞淋巴瘤免疫相关研究进展
Immunological advances in Epstein-Barr virus positive diffuse large B-cell lymphoma
张森森 1周生余2
作者信息
- 1. 山东省潍坊市中医院肿瘤科,潍坊 261000
- 2. 国家癌症中心 国家肿瘤临床医学研究中心 中国医学科学院北京协和医学院肿瘤医院内科,北京 100021
- 折叠
摘要
EB病毒阳性弥漫大B细胞淋巴瘤(DLBCL)是EB病毒阳性的克隆性B细胞淋巴增殖性疾病,是一种罕见的侵袭性B细胞淋巴瘤.其发病率较低且存在地区分布差异,缺乏多中心、高质量的前瞻性临床研究,因此目前对该病认识不足.文章对EB病毒阳性DLBCL的免疫相关机制进行综述,以期为进一步的临床研究和治疗提供有价值的参考意见.
Abstract
Epstein-Barr virus positive diffuse large B-cell lymphoma(DLBCL)is a clonal B-cell lymphoproliferative disorder with positive Epstein-Barr virus,which is a rare and aggressive B-cell lymphoma.Due to its low incidence and regional disparities in distribution,there is a lack of multicenter,high-quality prospective clinical studies,and the current understanding of this disease is still insufficient.The article reviews the immunological mechanisms associated with Epstein-Barr virus positive DLBCL,aiming to provide valuable insights for further clinical research and treatment.
关键词
EB病毒/弥漫大B细胞淋巴瘤/程序性死亡配体1/免疫衰老/免疫逃逸Key words
Epstein-Barr virus/Diffuse large B-cell lymphoma/Programmed death-ligand 1/Immune senescence/Immune escape引用本文复制引用
出版年
2024
NETL
NSTL
万方数据