中国肿瘤临床与康复2024，Vol.31Issue(12) ：784-790.DOI:10.13455/j.cnki.cjcor.113494-2024-2024-0248

基于化疗诱导恶心呕吐分级的结构性营养护理对胃癌根治术后化疗患者免疫功能和营养状态以及生活质量的影响

Effect of structural nutritional care based on CINV grade on immune function,nutritional status and quality of life of patients undergoing chemotherapy after radical resection of gastric cancer

黄宇 苏巧珍 袁从雯 丁思凡 余欢欢
中国肿瘤临床与康复2024，Vol.31Issue(12) ：784-790.DOI:10.13455/j.cnki.cjcor.113494-2024-2024-0248
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基于化疗诱导恶心呕吐分级的结构性营养护理对胃癌根治术后化疗患者免疫功能和营养状态以及生活质量的影响

Effect of structural nutritional care based on CINV grade on immune function,nutritional status and quality of life of patients undergoing chemotherapy after radical resection of gastric cancer

黄宇 1苏巧珍 1袁从雯 1丁思凡 1余欢欢1
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作者信息

  • 1. 蚌埠医科大学第一附属医院肿瘤外科,蚌埠 233000
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摘要

目的 分析基于化疗诱导恶心呕吐(CINV)分级的结构性营养护理对胃癌根治术后化疗患者免疫功能、营养状态及生活质量的影响.方法 回顾性分析2022年9月至2023年9月在蚌埠医科大学第一附属医院肿瘤外科接受胃癌根治术、且住院化疗的74例胃癌患者资料,其中男43例,女31例;年龄42～70岁.采用常规营养护理(对照组)37例,采用基于CINV分级的结构性营养护理(研究组)37例.比较两组患者护理前后的营养指标情况、免疫功能指标情况、生活质量以及护理满意度.结果 护理后,研究组胃癌患者的预后营养指数(55.60％±3.65％)较对照组明显升高(47.33％±3.03％,P＜0.001);研究组胃癌患者的CD4+T淋巴细胞比例(47.32％±3.15％)和CD4+/CD8+(2.52±0.69)均明显高于对照组(分别为39.25％±2.79％和1.66±0.35,均P＜0.001),研究组胃癌患者的CD8+T淋巴细胞(17.32％±1.20％)比例明显低于对照组(20.03％±1.55％,P＜0.001);研究组患者的生活质量指数量表各维度得分均明显高于对照组(均P＜0.001);研究组患者对护理的满意度为94.6％,明显高于对照组(75.7％,P＜0.001).结论 基于CINV分级的结构性营养护理干预,可以提升胃癌根治术后化疗患者的免疫功能,改善患者营养状态和生活质量,并提升患者对护理的满意度,具有较好的应用前景.

Abstract

Objective To analyze the effects of structural nutrition care based on CINV grade on the immune function,nutritional status and prognosis of patients undergoing chemotherapy after radical gastric cancer.Methods Data of 74 patients with gastric cancer who underwent radical gastrectomy and received inpatient chemotherapy in the Department of Tumor Surgery,the First Affiliated Hospital of Bengbu Medical University from September 2022 to September 2023 were retrospectively analyzed,including 43 males and 31 females.Age 42～70 years old.37 cases received conventional nutrition nursing(control group)and 37 cases received structural nutrition nursing(study group)based on CINV classification.The nutritional indexes,immune function indexes,quality of life and nursing satisfaction after nursing were compared between the two groups.Results After nursing,the prognostic nutritional index of gastric cancer patients in the study group(55.60％±3.65％)was significantly higher than that in the control group(47.33％±3.03％,P＜0.001).The CD4+T lymphocyte ratio(47.32％±3.15％)and CD4+/CD8+(2.52±0.69)of gastric cancer patients in the study group were significantly higher than those in the control group(39.25％±2.79％and 1.66±0.35,respectively,P＜0.001).The percentage of CD8+T lymphocytes in the study group(17.32％±1.20％)was significantly lower than that in the control group(20.03％±1.55％,P＜0.001).The quality of life index scores of the study group were significantly higher than those of the control group(all P＜0.001).The satisfaction rate of patients in the study group was 94.6％,which was significantly higher than that in the control group(75.7％,P＜0.001).Conclusion The structural nutritional nursing intervention based on CINV grade can improve the immune function of patients undergoing chemotherapy,improve the nutritional status and nutritional status and quality of life of patients,and significantly increase nursing satisfaction,demonstrating promising application prospects..

关键词

化疗诱导恶心呕吐/结构性营养护理/胃癌根治术/免疫功能/营养状态

Key words

Chemotherapy-induced nausea and vomiting/Structural nutritional care/Radical gastric cancer/Immune function/Nutritional status

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出版年

2024
中国肿瘤临床与康复
中国癌症研究基金会

中国肿瘤临床与康复

影响因子：0.887
ISSN：1005-8664
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