An experimental study on the effect of Songqi capsule on the stress ability and antioxidase in mice
Objective To study the effect of Songqi capsule on the stress ability,the activity of superoxide dismutase（SOD） and the content of malondialdehyde（MDA） in blood,and to further investigate the anti-aging mechanism of action of Songqi capsule.Methods Mice were randomly divided into large dose group,small dose group and control group.The experiments of fatigue-resistance in swim,cold resistance and hypoxia-resistance in normal pressure were performed on mice.The contents of MDA and SOD in blood in mice of the three groups were determined.Results Songqi capsule enhanced the cold resistance ability,decreased the death rate,extended the time of actively swimming,enhanced fatigue-resistance ability,prolonged the hypoxia-resistance time in normal pressure and raised hypoxia-resistance ability of mice.Songqi capsule obviously increased the content of SOD and reduced the content of MDA in mice comparing those in control group（P0.01）.Conclusion Songqi capsule has perfect antioxidation and anti-aging effect in vivo.
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