首页|An Overview of Epigenetics in Chinese Medicine Researches

An Overview of Epigenetics in Chinese Medicine Researches

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Chinese medicine (CM) has contributed to human health care for several thousand years and is still popular in Asian countries.But the mechanisms underlying CM remain obscure,and need to be clarified by modem biological subjects and methods.Recently,CM researches on epigenetics have gained obvious improvement following rapidly developed molecular technologies.In this review,we revealed mutual characteristics of epigenetics and CM,such as holism,yin-yang dynamic nature,reversibility and balance,and visceral manifestation.Moreover,epigenetic modifications,including DNA methylation,histone post-transcriptional modifications,micro RNA interference,etc.may help explore the molecular basis of CM syndrome classification,and mechanisms of Chinese herbal medicine (CHM),CHM compounds and Chinese herbal formulae activities.Meanwhile,CM and epigenetics might promote each other and jointly develop following the continuous progress of epigenetics in CM researches.

Chinese medicineepigeneticsmethylationhistone modificationChinese herbal medicineChinese herbal formulaChinese medicine syndrome

HU Xue-qing、SU Shi-bing

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Research Center for Traditional Chinese Medicine Complexity System, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China

Key Program of National Natural Science Foundation of China"085" First-Class Discipline Construction Innovation Science and Technology Support Project of Shanghai University of TraditionaE-Institutes of Shanghai Municipal Education Commission

81330084085ZY1206E03008

2017

10.1007/s11655-016-2274-y

中国结合医学杂志(英文版)
中国中西医结合学会 中国中医研究院

中国结合医学杂志(英文版)

CSCDSCI
影响因子：1.056
ISSN：1672-0415
年,卷(期)：2017.23(9)
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