首页|Chemical Composition,Pharmacological Effects and Clinical Applications of Cinobufacini

Chemical Composition,Pharmacological Effects and Clinical Applications of Cinobufacini

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Chinese medicine cinobufacini is an extract from the dried skin of Bufo bufo gargarizans Cantor,with active ingredients of bufadienolides and indole alkaloids.With further research and clinical applications,it is found that cinobufacini alone or in combination with other therapeutic methods can play an anti-tumor role by controlling proliferation of tumor cells,promoting apoptosis,inhibiting formation of tumor neovascularization,reversing multidrug resistance,and regulating immune response;it also has the functions of relieving cancer pain and regulating immune function.In this paper,the chemical composition,pharmacological effects,clinical applications,and adverse reactions of cinobufacini are summarized.However,the extraction of monomer components of cinobufacini,the relationship between different mechanisms,and the causes of adverse reactions need to be further studied.Also,high-quality clinical studies should be conducted.

cinobufacinichemical compositionChinese medicinepharmacological effectclinical applicationadverse effect

ZUO Qian、XU Ding-qiao、YUE Shi-jun、FU Rui-jia、TANG Yu-ping

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Key Laboratory of Shaanxi Administration of Traditional Chinese Medicine for TCM Compatibility,Shaanxi University of Chinese Medicine,Xi'an(712046),China

国家自然科学基金Inheritance and Innovation of Traditional Chinese Medicine and Key Scientific Research Project of"Qin Medicine"Development of ShSubject Innovation Team of Shaanxi University of Chinese Medicine

822740842021-02-22-0072019-YL10

2024

中国结合医学杂志(英文版)
中国中西医结合学会 中国中医研究院

中国结合医学杂志(英文版)

CSTPCD
影响因子:1.056
ISSN:1672-0415
年,卷(期):2024.30(4)
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