首页|Disease-Related Factors Associated with Acupuncture Response in Patients with Chronic Tension-Type Headache:A Secondary Analysis of A Randomized Controlled Trial

Disease-Related Factors Associated with Acupuncture Response in Patients with Chronic Tension-Type Headache:A Secondary Analysis of A Randomized Controlled Trial

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Objective:To explore the demographic and disease-related factors associated with acupuncture response in patients with chronic tension-type headache(CTTH).Methods:Using data from the randomized clinical trial(218 cases)consisting of 4 weeks of baseline assessment,8 weeks of treatment,and 24 weeks of follow-up,participants were regrouped into responders(at least a 50%reduction in monthly headache days at week 16 compared with baseline)and non-responders.Twenty-three demographic and disease-related factors associated with acupuncture response in 183 participants were analyzed by multivariable logistic regression.Results:One hundred and nineteen(65.0%)participants were classified as responders.Four factors were significantly independently associated with acupuncture response,including treatment assignment,headache intensity at baseline,and 2 domains[general health(GH)and social functioning(SF)]from the 36-Item Short Form Health Survey quality of life questionnaire.Treatment assignment was associated with non-response:participants receiving true acupuncture were 3-time more likely to achieve a CTTH response than those receiving superficial acupuncture[odds ratio(OR)0.322,95% confidence interval(CI)0.162 to 0.625,P=0.001].Compared with patients with mild-intensity headache,patients with moderate-intensity headache were twice as likely to respond to acupuncture(OR 2.001,95% CI 1.020 to 4.011,P=0.046).The likelihood of non-response increased by 4.5%with each unit increase in the GH grade(OR 0.955,95% CI 0.917 to 0.993,P=0.024)while decreased by 3.8% with each unit increase in the SF grade(OR 1.038,95% CI 1.009 to 1.069,P=0.011).Conclusions:Greater headache intensity,lower GH score,and higher SF score were associated with better acupuncture responses in CTTH patients.These 3 factors require independent validation as predictors of acupuncture effectiveness in CTTH.

acupuncturechronic tension-type headachelogistic regressionquality of lifeChinese medicine

CAO Wei、WANG Lu、HOU Ting-hui、SHI Yun-zhou、ZHENG Qian-hua、ZHENG Hui、ZOU Zi-hao、QIN Di、YANG Qian、CHEN Si-jue、WANG Hai-yan、XIAO Xian-jun、LI Ying

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Department of Acupuncture and Moxibustion,Chengdu University of Traditional Chinese Medicine,Chengdu(610000),China

Acupuncture and Moxibustion School of Health Preservation and Rehabilitation,Chengdu University of Traditional Chinese Medicine,Chengdu(610000),China

International Cooperation Program of Science and Technology Department of Sichuan Province,China

2016HH0007

2024

中国结合医学杂志(英文版)
中国中西医结合学会 中国中医研究院

中国结合医学杂志(英文版)

CSTPCD
影响因子:1.056
ISSN:1672-0415
年,卷(期):2024.30(8)