Clinical observation of orthopedics No.Ⅰ heji combined with rivaroxaban tablets in the treatment of limb swelling and lower limb venous thrombosis after intertrochanteric fracture of femur
Clinical observation of orthopedics No.Ⅰ heji combined with rivaroxaban tablets in the treatment of limb swelling and lower limb venous thrombosis after intertrochanteric fracture of femur
Objective To investigate the clinical observation of orthopedics No.Ⅰ heji combined with rivaroxaban in the treatment of limb swelling and lower limb venous thrombosis after intertrochanteric fracture of femur.Methods A total of 72 patients with lower extremity venous thrombosis after intertrochanteric fracture in our hospital were selected,and divided into observation group and control group with 36 patients in each group.36 patients in control group were treated with rivaroxaban tablets,and observation group was treated with orthopedic No.Ⅰ heji on the basis of control group.The clinical efficacy,thromboelasticity chart indexes(coagulation response time(R),coagulation formation time(K),coagulation Angle(α),maximum thrombotic intensity(MA)and comprehensive coagulation index(CI))of the two groups before and after treatment were observed.Coagulation indicators(PT),activated partial thrombin time(APTT),plasma fibrinogen(FIB),thrombin time(TT),D-dimer,color ultrasound results of lower limb veins(bilateral femoral vein blood flow velocity),swelling degree of affected limb(circumference of knee joint,10 cm above patella,10 cm below patella).Results After treatment,observation group total effective rate was 94.44％,higher than that of control group 75％(P＜0.05).After treatment,the values of thrombus elasticity chart R and K were higher than before treatment,and the values of α,MA and CI were lower than before treatment(P＜0.05).the values of coagulation index PT,APTT and TT were higher than those before treatment,and the values of FIB and D-dimer were lower than those before treatment(P＜0.05).the blood flow velocity of limb femoral vein in both groups was faster than that before treatment(P＜0.05).knee joint,the 10 cm circumferential diameter above patella and the 10 cm circumferential diameter below patella were all decreased in 2 groups compared with before treatment.All of these project the observation group was better han the control group(P＜0.05).Conclusion The combination of orthopedics No.Ⅰ heji and rivaroxaban can effectively reduce the degree of swelling of the affected limb after the operation of intertrochanteric fracture of femur,reduce the formation of lower limb venous thrombosis,improve the velocity of lower limb venous blood flow,and improve coagulation and thromboelasticity index,with significant clinical efficacy.
关键词
骨科Ⅰ号合剂/利伐沙班/股骨粗隆间骨折术后/患肢肿胀程度/下肢静脉血栓
Key words
Orthopedics No.Ⅰ heji/rivaroxaban/postoperative operation of intertrochanteric fracture of femur/the degree of swelling of the affected limb/lower limb venous thrombosis
维普
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