Observation on clinical efficacy of Yinchenhao decoction combined with conventional treatment in patients with obstructive jaundice of heat heavier than dampness syndrome
Observation on clinical efficacy of Yinchenhao decoction combined with conventional treatment in patients with obstructive jaundice of heat heavier than dampness syndrome
Objective To explore the clinical efficacy of Yinchenhao decoction in combination with conventional treatment for patients suffering from obstructive jaundice and hot over dampness syndrome.Methods 96 patients with obstructive jaundice admitted to Nankai Hospital in Tianjin from June 2020 to December 2021 were selected,and they were randomly divided into a control group and a treatment group,with 48 individuals in each group.The control group received conventional treatment(ATP adenosine uridine triphosphate enteric-coated capsules)while the treatment group was given Yinchenhao Tang in addition to the conventional treatment.The treatment course lasted for one week.The study measured the following indicators:jaundice index(TBIL and DBIL),liver function(GGT and ALT),blood bile acid(TBA),urine bile acid,traditional Chinese medicine syndrome score and clinical efficacy.Results Compared to the first day after surgery,both groups of patients exhibited a decrease in TBIL,DBIL,ALT,GGT and blood TBA levels on the 7th day after relieving biliary obstruction(P＜0.05).The treatment group showed a more significant decrease when compared to the control group(P＜0.05).Additionally,both groups of patients experienced an increase in urinary TBA levels and 24-hour urine volume(P＜0.05),with the treatment group demonstrating a more significant increase compared to the control group(P＜0.05).The treatment group displayed a lower quantitative score of traditional Chinese medicine symptoms in comparison to the control group(P＜0.05).Furthermore,the treatment group exhibited a higher total effective rate of disease treatment than the control group(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion Relief of biliary obstruction in individuals with obstructive jaundice and hot over dampness syndrome can be attained through Yinchenhao decoction in combination with conventional treatment.This protocol can promote bile acid excretion,alleviate jaundice and protect liver function.Additionally,it can effectively improve traditional Chinese medicine clinical symptoms and enhance the clinical efficacy of patients'treatments with good tolerability.
维普
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