Objective To study the clinical efficacy of Bujindan combined with arthroscopic surgery for repairing rotator cuff injuries with osteoporosis in elderly patients and its impact on metabolic indicators.Methods 60 patients with rotator cuff injury and osteoporosis admitted to our hospital from January 2020 to June 2022 were selected.The patients were divided into two groups.The rotator cuff injury was repaired by total arthroscopic surgery in both groups.Observation group was supplemented with Bujindan orally after operation.University of California at Los Angeles(UCLA)score,the American Society for Shoulder and Elbow Surgery(ASES)score,Constant-Mueley score,shoulder anterior flexor motion,external rotation motion,abductor motion,visual analogue pain(VAS)score,complications and leukocytes were compared between the two groups before and after surgery.The values of hormone(IL)-37,IL-6,matrix metalloenzyme(MMP)-2,bone mineral density(BMD)and bone.Results After treatment,the postoperative UCLA score,ASES score,Constant-Mueley score,shoulder joint anterior flexion motion,external rotation motion and abduction motion of the two groups were significantly better than before intervention.The ASES score of observation group was significantly higher than that of control group(P<0.05).Postoperative 48 h and 72 h VAS scores in two groups were significantly lower than those before surgery(P<0.05).Observation group 24 h after operation VAS scores,48 h and 72 h were significantly lower than those of control group(P<0.05).The total incidence of complications was 13.33%in the observation group and 33.33%in the control group,with significant difference between the two groups(P<0.05).After treatment,IL-37 was increased in both groups,and the observation group was significantly higher than the control group(P<0.05).IL-6 and MMP-2 were lower than those in the observation group.The difference was significant(P<0.05).BMD values increased in both groups after treatment.The BMD values of femoral neck,lumbar spine and trochanteric region in observation group were significantly higher than those in control group(P<0.05).The serum calcium level in both groups was increased,and the observation group was significantly higher than that in the control group,and the serum phosphorus and alkaline phosphatase levels in both groups were decreased.The levels of serum phosphorus and alkaline phosphatase in observation group were significantly lower than those in control group(P<0.05).Conclusion The use of total arthroscopic rotator cuff repair combined with Bujindan can effectively improve the UCLV score,ASES score,Constant Mueley score,and bone and joint function and score of elderly patients with rotator cuff injury and osteoporosis.It can improve the degree of pain and regulate osteoporosis,inhibiting the inflammatory response of the body,while also having a lower overall incidence of complications,which is worthy of clinical selection.