Research Progress on Intestinal Immunity in Ulcerative Colitis
Ulcerative colitis(UC)is a chronic nonspecific disease of the colon and rectum whose etiology is not well defined.UC is closely related to intestinal immunity.Intestinal-associated lymphoid tissue and lamina propria contain abundant immune cells,which play an important role in maintaining intestinal immune homeostasis.The imbalance of T helper cell(Th)17/T regulatory cell(Treg)was proved to be relative to intestinal immune homeostasis of UC,which was affected by metabolic reprogramming of cells.To provide a reference for UC research,this paper mainly reviewed the studies from three aspects:enteric-associated lymphoid tissue and various immune factors in lamina propria related to UC,metabolic reprogramming of Th17/Treg cells,and traditional Chinese medicine immune regulation treatment of UC.
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