Analysis of the Characteristics of Skin Lesions in Patients with Atopic Dermatitis with Spleen Deficiency and Dampness Accumulation Syndrome
Objective To explore the characteristics of skin lesions in patients with spleen deficiency and dampness accumulation syndrome of atopic dermatitis by combination of data mining and clinical cross-sectional study.Methods The relevant modern clinical literature were searched since the establishment of the databases to October 31st,2021.EXCEL 2017 database was established and descriptive analysis of frequency,correlation analysis was conducted.In addition,patients with atopic dermatitis from the dermatology department of Guangdong Hospital of Traditional Chinese Medicine were recruited and divided into two groups.Demographic data and the collection table of skin lesion characteristics were filled in.Non-parameter test and binary logistic regression analysis were analyzed by SPSS 27.0.Results A total of 288 articles were included,the most common manifestations of spleen deficiency syndrome included papule,scales,pruritus,erosion and exudation.The correlation analysis indicated that papules,pruritus,erosion and exudation had strong correlation with spleen deficiency dampness syndrome.A total of 152 patients were included in clinical study.The difference analysis indicated that there were statistical differences between two groups in roughness,scaling and flushing(P<0.05).The results of single factor regression suggested that roughness,scaling and flushing could significantly affect whether patients had spleen deficiency dampness syndrome(P<0.05),and the results of multivariate regression indicated that only flushing was a significant factor of non-spleen deficiency dampness syndrome(P<0.05).Conclusion There were no significant features in skin lesions of atopic dermatitis patients with spleen deficiency dampness syndrome,however,both"dampness"and"dryness"skin lesions features can appear simultaneously.
Atopic dermatitisSyndromeFeatures of skin lesionsSpleen deficiency and dampness accumulation syndrome
NETL
NSTL
万方数据
维普
