Prescription Rules of Stomachache of Famous Traditional Chinese Doctors Based on Data Mining
Objective We explored the famous TCM doctors'prescription regularity of the treatment for chronic atrophic gastritis with stomachache via data mining,to offer further support for clinical diagnosis and treatment.Methods With ancient and modern medical case cloud platforms,we searched for the case of atrophic gastritis with a stomachache in the"famous doctor's medical record library",built Excel to extract relevant information,standardized the collection of data,and applied data mining software for frequency statistics,association analysis,cluster analysis,and complex network analysis.Results With screening,we added up to 105 cases,114 Chinese herbal compounds,and 196 traditional Chinese medicines.The results showed that lack of stomach Yin syndrome was the most common syndrome,four properties were given priority to warm and flat,and five tastes were based on sweet,bitter,and pungent.The channel tropism of medicine was centered on the spleen,stomach,liver,and lungs.Traditional Chinese medicines which frequency>20 amount to 25,such as Radix Paeoniae Alba,Radix Glycyrrhizae,Atractylodes,Poria Cocos,Codonopsis,Salvia Miltiorrhiza,Dried Tangerine or Orange Peel,Astragalus Root,Spreading Hedyotis Herb,etc.Through the association rules analysis,a total of 16 traditional Chinese medicine pairs were used,such as Radix Paeoniae Alba-Radix Glycyrrhizae,Poria Cocos-Atractylodes,Dried Tangerine or Tangerine Peel,etc.Association rules between medicine and syndrome showed that symptoms of lack of stomach Yin commonly used Radix Paeoniae Alba,Caulis Dendrobii,Radix Ophiopogonis,Ebony,etc;syndrome of the weakness of the spleen and the stomach commonly used Atractylodes,Dangshen,and Poria Cocos;syndrome of damp heat in the spleen and the stomach commonly used Chinese Goldthread,Pinellia,Atractylodes,Spreading Hedyotis Herb,etc.Through cluster analysis,drugs with a higher frequency were classified into 6 types.The core drugs were composed of 32 Chinese herbs through complex network analysis.Conclusion It could be found that the clinical symptoms of the disease were complex and varied,intermingled deficiency and excess.Therapeutic principles and methods included nourishing Yin relieving spasms,invigorating the spleen and soothing the liver,heat-clearing and damp-drying,and benefiting Qi for activating blood circulation,etc.Prescriptions used included Shaoyao Gancao decoction,Sijunzi decoction,Banxia Xiexin decoction,and modification according to symptoms.