Research on the Medication Patterns for the Differentiation and Treatment of Scarlet Fever in Yi Hou Qian Lun Based on Data Mining
Objective To explore the characteristics and laws of Xia Yun,a laryngologist of Qing dynasty,in the treatment of scarlet fever.Methods We manually searched the internal and external prescriptions for scarlet fever in Yi Hou Qian Lun and establised databases seperately.Statistical analysis,correlation analysis and hierarchical cluster analysis in the cloud platform of ancient and modern medical records(V2.3.5)were used to explore the frequency,efficacy,four natures,five flavours,meridian distribution,common drug pairs and core drug combination rules of traditional Chinese medicine in internal and external prescriptions.Results There were 64 therapeutic prescriptions for scarlet fever in Yi Hou Qian Lun,including 41 prescriptions for internal use and 23 prescriptions for external use.In the internal prescriptions,Figwort was the most frequently used traditional Chinese medicine.The drug efficacy was mainly based on dispelling wind and heat.The four natures,five flavours and meridian distribution of drugs belonged to the cold,sweet and lung meridian.The common drug pair was Rehmannia glutinosa and Dwarf lilyturf root.Three kinds of core prescriptions were obtained by cluster analysis.In external prescriptions,Borneol was the most frequently used traditional Chinese medicine.The drug efficacy was mainly to clear away heat and detoxify.The four natures,five flavours and meridian distribution of drugs belonged to the cold,bitter,and lung meridian.The common drug pair was Borax and Borneol.Three kinds of core prescriptions were obtained by cluster analysis.Conclusion The internal and external prescriptions for the treatment of scarlet fever in Yi Hou Qian Lun reflected Xia Yun's understanding of the pathogenesis and location of scarlet fever.It embodied the treatment principle of"clearing away toxins,cooling and relieving heat",and provided a reference for the treatment of scarlet fever.
Data miningYi Hou Qian LunScarlet feverMedication rule