首页|RDW、BNP及尿酸与慢性心力衰竭中医证候的相关性研究

RDW、BNP及尿酸与慢性心力衰竭中医证候的相关性研究

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目的:探讨红细胞分布宽度(RDW)、B型利钠肽(BNP)及尿酸(UA)与慢性心力衰竭(CHF)患者中医证候的相关性.方法:选择2021年1月-2023年1月本院治疗的106例CHF患者,入组后均进行中医辨证分型,另选取同期健康体检患者60例纳入健康对照组.所有患者入组后均检测RDW、BNP及UA水平.对比对照组、CHF组及不同证候患者RDW、BNP、UA水平,分析RDW、BNP及UA水平与CHF中医证候的相关性.结果:CHF组患者RDW、BNP及UA水平均明显高于健康对照组(P=0.000).106例CHF患者中,心肺气虚证16例、气阴两亏证31例、心肾阳虚证22例、气虚血瘀证19例、阳虚水泛证18例.各证候CHF患者RDW、BNP及UA水平均明显高于对照组,且各证候CHF患者RDW、BNP及UA水平两两比较,差异均存在统计学意义(P=0.000).各个证型患者血RDW、BNP及UA水平由低到高为:心肺气虚证<气阴两亏证<气虚血瘀证<心肾阳虚证<阳虚水泛证.结论:血RDW、BNP及UA水平与CHF中医辨证存在一定程度的相关性,可用作中医辨证分型的客观化参考指标.
Correlation between RDW,BNP and Uric Acid and TCM Syndromes in Chronic Heart Failure
Objective:To analyze the correlation of red blood cell distribution width(RDW),type B natri-uretic peptide(BNP)and uric acid(UA)and Differentiation of syndromes in patients with chronic heart failure(CHF).Methods:106 CHF patients hospitalized from January 2021 to January 2023 were included in the CHF group,and 60 patients with healthy examination in the same period were included in the control group.All pa-tients'RDW,BNP and UA levels were tested after enrollment.RDW,BNP and UA levels of control and CHF groups were compared,and the correlation between RDW,BNP and UA and differentiation of syndromes in CHF were analyzed.Results:The RDW,BNP and UA levels were significantly higher in the CHF group than those in the control group(P=0.000).According the dialectical classification of CHF,16 cases with qi deficiency of lung and heart,31 cases with qi and yin deficiency,22 cases with yang deficiency of heart and kidney,19 cases with qi deficiency and blood stasis,and 18 cases with yang deficiency and water diffusion syndrome.The RDW,BNP and UA levels of CHF patients were significantly higher than those of the control group(P=0.000).The RDW,BNP and UA levels of each syndrome ranged from low to high as:heart and lung qi deficiency syndrome<qi and yin deficiency syndrome<qi deficiency and blood stasis syndrome<yang deficiency of heart and kidney syndrome<yang deficiency and water diffusion syndrome.Conclusion:There is some degree of correlation be-tween blood RDW,BNP and UA levels and CHF TCM syndromes,which can be used as an objective reference index for TCM differentiation of syndromes.

chronic heart failureChinese medicine syndromescorrelationRDWBNPUA

虞颖茜、丰俊鹏、王露、王艳敏

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平顶山市中医医院心病科·河南 平顶山 467000

慢性心力衰竭 中医证候 相关性 红细胞分布宽度 B型利钠肽 尿酸

河南中医药传承与创新人才工程(仲景工程)中医药拔尖人才

豫卫中医函[2021]15号

2024

中国中医药科技
中华中医药学会

中国中医药科技

影响因子:1.156
ISSN:1005-7072
年,卷(期):2024.31(4)
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