Application Evaluation of Targeted Synthetic Disease-Modifying Anti-Rheumatic Drugs in Rheumatoid Arthritis
In recent years,numerous novel drugs for rheumatoid arthritis have been developed,including biological disease-modifying anti-rheumatic drugs(bDMARDs)and targeted synthetic disease-modifying anti-rheumatic drugs(tsDMARDs).Among them,tsDMARDs are widely used in clinic practice due to their favorable clinical efficacy,oral administration convenience and managable adverse reactions.This paper reviews the mechanism of action,clinical study,adverse reactions and listing status of tsDMARDs,in order to provide reference for clinical application.
rheumatoid arthritistargeted synthetic disease-modifying anti-rheumatic drugsclinical studymechanism of actionadverse drug reaction