中国合理用药探索2024,Vol.21Issue(1) :35-39.DOI:10.3969/j.issn.2096-3327.2024.01.007

度拉糖肽注射液相关的急性便秘1例与文献回顾

A Case of Dulaglutide Injection-Related Acute Constipation and Literature Review

董环 李雪 周鹏翔
中国合理用药探索2024,Vol.21Issue(1) :35-39.DOI:10.3969/j.issn.2096-3327.2024.01.007

度拉糖肽注射液相关的急性便秘1例与文献回顾

A Case of Dulaglutide Injection-Related Acute Constipation and Literature Review

董环 1李雪 1周鹏翔2
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作者信息

  • 1. 北京大学第三医院药剂科,北京 100191
  • 2. 北京大学第三医院药剂科,北京 100191;北京大学医学部药物评价中心,北京 100191
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摘要

本文报道了1例男性患者在使用度拉糖肽注射液超说明书用药用于减重治疗后发生的急性便秘,并进行了全面的文献分析与总结.患者在对症治疗后便秘症状减轻,减少度拉糖肽注射液剂量后未再出现便秘.本研究度拉糖肽注射液与急性便秘的关联性评价结果为"很可能",提示临床应用时应警惕急性便秘的发生.

Abstract

A male patient who experienced acute constipation after receiving anti-obesity therapy with Dulaglutide Injection was reported and a comprehensive literature analysis and summary was performed.The constipation was alleviated after symptomatic treatment and did not recur after dose reduction for Dulaglutide.As the relatedness between Dulaglutide Injection and acute constipation was judged as"probable",the drug should be used guarding against acute constipation in clinical practice.

关键词

度拉糖肽注射液/急性便秘/药品不良反应/文献回顾/药事服务

Key words

dulaglutide injection/acute constipation/adverse drug reactions/literature review/pharmaceutical services

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出版年

2024
中国合理用药探索
中国执业药师协会

中国合理用药探索

影响因子:0.62
ISSN:2096-3327
参考文献量34
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