首页|基于社区医院信息六级平台的非甾体抗炎药门诊用药评价

基于社区医院信息六级平台的非甾体抗炎药门诊用药评价

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目的:从真实世界数据出发,分析并评价某院2个时间段使用非甾体抗炎药(NSAIDs)的门诊患者分布特征、用药特点、用药情况等,为临床合理用药提供参考.方法:回顾性收集2021年12月1日~2022年1月15日(A时段)与2022年12月1日~2023年1月15日(B时段)期间某院门诊使用NSAIDs患者的性别、年龄等基本信息,梳理总结NSAIDs的品种、使用频率、用药天数等,并整理限定日剂量(DDD),计算用药频度(DDDs)、限定日费用(DDC)及药物利用指数(DUI)等,比较2个时间段NSAIDs的应用情况,选择重点药品进行用药分析与评价.结果:A与B时段分别有5600例与10 916例患者使用NSAIDs,2个时间段各自使用13种与28种药品.尤其在B时段出现了用药品种、用药量剧增现象,其中DDDs排名前3位的是阿司匹林肠溶片(规格100mg)、双氯芬酸钠双释放肠溶胶囊、布洛芬缓释胶囊;DDDs增幅居前3位的是布洛芬混悬液(929.05%)、布洛芬缓释胶囊(322.10%)、氨麻美敏片(Ⅲ)(319.92%).复方制剂的使用率上升至首位(39.22%).吲哚布芬片的DDC值最高(31.47元),阿司匹林肠溶片(规格25mg)DDC值最低(0.26元).大多数NSAIDs的DUI<1,提示该院NSAIDs使用基本合理.结论:在目标时间范围内,该院门诊NSAIDs使用基本合理.
Evaluation of Prescriptions of Non-Steroidal Anti-Inflammatory Drugs in Outpatient Department of Community Hospital Based on Six-Level Information Platform
Objective:To analyze and evaluate the distributional characteristics,medication characteristics and drug use of non-steroidal anti-inflammatory drugs(NSAIDs)of outpatient patients in a hospital based on the real-world data during the two time periods,so as to provide reference for clinical rational drug use.Methods:The basic data of patients prescribed with NSAIDs in the outpatient department of a hospital,from 01 December 2021 to 15 January 2022(time period A)and 01 December 2022 to 15 January 2023(time period B),were collected retrospectively,including sex and age.The varieties,frequency and days of drug use,and the defined daily dose(DDD)were summarized for NSAIDs,and the defined daily dose system(DDDs),defined daily cost(DDC)and drug utilization index(DUI)were calculated.The use of NSAIDs in the two periods was compared,and the analysis and evaluation of drug use were performed on the basis of medicines of key varieties.Results:NSAIDs were used by 5600 and 10 916 patients during the time period A and time period B,respectively,covering 13 and 28 varieties,respectively.The number of varieties and the amount of dose soared from time period B,during which,the top 3 medicines in terms of increase in DDDs were Aspirin Enteric-coated Tablets(strength 100 mg),Diclofenac Sodium Dual Release Enteric-coated Capsules and Ibuprofen Sustained-release Capsules,and the top 3 medicines with regard to the increase in DDDs were Ibuprofen Suspension(929.05%),Ibuprofen Sustained-release Capsules(322.10%),and Pracetamol,Pseudoephedrine Hydrochloride,Dextromethrophan Hydrobromide and Chlorphenamine Maleate Tablets(Ⅲ)(319.92%).The use rate of compound preparation rose to the first place(39.22%).The DDC value was the highest for Indobufen Tablets(31.47 yuan)whereas the lowest for Aspirin Enteric-coated Tablets(25 mg)(0.26 yuan).The most DUI of NSAIDs was<1,indicating that the NSAIDs was used rationally in the hospital.Conclusions:The prescriptions of NSAIDs in the outpatient department of the hospital were basically rational within the target time period.

information platformnon-steroidal anti-inflammatory drugsdefined daily dose systemdefined daily costdrug use evaluation

金蕾、杨耀芳、汤阳、宦红梅、沈真原

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上海市闵行区古美社区卫生服务中心,上海 201102

复旦大学附属上海市第五人民医院,上海 200240

复旦大学附属上海市公共卫生临床中心,上海 201508

信息平台 非甾体抗炎药 用药频度 限定日费用 用药评价

2023年闵行区自然科学研究课题

2023MHZ086

2024

中国合理用药探索
中国执业药师协会

中国合理用药探索

影响因子:0.62
ISSN:2096-3327
年,卷(期):2024.21(1)
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